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Biocatalysis
Bioinorganic Chemistry
Biomacromolecule-Ligand Interactions
Biomimetic Chemistry
Cell Signalling & Trafficking Structures
Chemical Biology of the Cell
Directed Molecular Evolution
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Structure: RNA
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Structure: Transcription & Translation
Theory & Simulation


 MOST VIEWED PAPERS | Biochemistry | calculated on 2 December 2008
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1
Must Read
F1000 Factor 6.6

Hypothesis
New Finding
 A unique cell division machinery in the Archaea.
Lindås AC, Karlsson EA, …, Ettema TJ, Bernander R
Proc Natl Acad Sci U S A 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | William Margolin / Linda Amos / Harold Erickson / Mohan Balasubramanian with Ramanujam Srinivasan and Mithilesh Mishra
First evaluation 13 Nov 2008 | Latest evaluation 26 Nov 2008
 
2
Exceptional
F1000 Factor 10.4

Hypothesis
New Finding
 Species-specific transcription in mice carrying human chromosome 21.
Wilson MD, Barbosa-Morais NL, …, Tavaré S, Odom DT
Science 2008 Oct 17 322(5900):434-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yoav Gilad / Kenneth Zaret / Deyou Zheng / Julin Maloof with Jose M. Jimenez-Gomez / Lin Chen with Reza Kalhor / Tom Misteli with Evi Soutoglou
First evaluation 13 Oct 2008 | Latest evaluation 24 Nov 2008
 
3
Must Read
F1000 Factor 6.4

New Finding
Tech Advance
Novel Drug Target
 Chemical control of protein stability and function in living mice.
Banaszynski LA, Sellmyer MA, …, Wandless TJ, Thorne SH
Nat Med 2008 Oct 14(10):1123-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ken Irvine with Yongqiang Feng / Thomas W. von Geldern
First evaluation 20 Nov 2008 | Latest evaluation 21 Nov 2008
 
4
Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
 Crystal Structure of a Ten-Amino Acid Protein.
Honda S, Akiba T, …, Odahara T, Harata K
J Am Chem Soc 2008 Oct 25 0 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Torleif Härd
Evaluated 12 Nov 2008
 
5
Must Read
F1000 Factor 6.0

New Finding
 X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus.
Bornholdt ZA, Prasad BV
Nature 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | Samuel Butcher
Evaluated 13 Nov 2008
 
6
Exceptional
F1000 Factor 8.0

Hypothesis
New Finding
 Protein-folding location can regulate manganese-binding versus copper- or zinc-binding.
Tottey S, Waldron KJ, …, Dennison C, Robinson NJ
Nature 2008 Oct 23 455(7216):1138-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Angela Wilks / John Helmann
First evaluation 3 Nov 2008 | Latest evaluation 11 Nov 2008
 
7
Exceptional
F1000 Factor 10.1

Hypothesis
New Finding
Tech Advance
 Structure of a complex of the ATPase SecA and the protein-translocation channel.
Zimmer J, Nam Y, Rapoport TA
Nature 2008 Oct 16 455(7215):936-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Manfred Schliwa / Ian Collinson / Art Horwich / Martin Pool
First evaluation 31 Oct 2008 | Latest evaluation 28 Nov 2008
 
8
Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 A Role for the ESCRT System in Cell Division in Archaea.
Samson RY, Obita T, …, Williams RL, Bell SD
Science 2008 Nov 13 [abstract on PubMed] [related articles] [full text]
Selected by | Linda Amos
Evaluated 17 Nov 2008
 
9
Recommended
F1000 Factor 3.0

Tech Advance
Novel Drug Target
 Generating Arrays with High Content and Minimal Consumption of Functional Membrane Proteins.
Majd S, Mayer M
J Am Chem Soc 2008 Nov 1 0 [abstract on PubMed] [related articles] [full text]
Selected by | Ross Weatherman
Evaluated 17 Nov 2008
 
10
Must Read
F1000 Factor 6.0

Confirmation
Tech Advance
Novel Drug Target
 Design and synthesis of highly sensitive fluorogenic substrates for glutathione S-transferase and application for activity imaging in living cells.
Fujikawa Y, Urano Y, …, Inoue H, Nagano T
J Am Chem Soc 2008 Nov 5 130(44):14533-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hening Lin
Evaluated 17 Nov 2008

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