7-Jan-2009
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All F1000 Biology
Immunology
Top 10s
Immunology
Current Top 10
All Time Top 10
Most-viewed Top 10
Hidden Jewels Top 10
Sections Covered
Allergy & Hypersensitivity
Antigen Processing & Recognition
Autoimmunity
Genetics of the Immune System
Immune Response
Immunity to Infections
Immunomodulation
Innate Immunity
Leukocyte Activation
Leukocyte Development
Leukocyte Signalling & Gene Expression
Related Sections
Cellular Microbiology & Pathogenesis
Immunopharmacology & Hematologic Pharmacology
MOST VIEWED PAPERS | Immunology | calculated on 7 January 2009
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1
Exceptional
F1000 Factor
9.0
New Finding
Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells.
Ng G, Sharma K, …, Amrein MW, Shi Y
Immunity
2008 Nov
29
(5):807-18 [
abstract on PubMed
] [
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full text
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Selected by
| Dan Conrad
Evaluated 2 Jan 2009
2
Exceptional
F1000 Factor
9.0
New Finding
Tech Advance
Novel Drug Target
Deliberately provoking local inflammation drives tumors to become their own protective vaccine site.
Jackaman C, Lew AM, …, Robinson BW, Nelson DJ
Int Immunol
2008 Nov
20
(11):1467-79 [
abstract on PubMed
] [
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full text
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Selected by
| Etienne Joly
Evaluated 9 Dec 2008
3
Exceptional
F1000 Factor
9.0
Hypothesis
New Finding
Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells.
Hill JA, Hall JA, …, Mathis D, Benoist C
Immunity
2008 Nov
29
(5):758-70 [
abstract on PubMed
] [
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Selected by
| Laurence Morel
Evaluated 22 Dec 2008
4
Must Read
F1000 Factor
6.0
Confirmation
New Finding
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9.
Park B, Brinkmann MM, …, Kim YM, Ploegh HL
Nat Immunol
2008 Dec
9
(12):1407-14 [
abstract on PubMed
] [
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full text
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Selected by
| Colin Watts with Michele West
Evaluated 2 Jan 2009
5
Must Read
F1000 Factor
6.0
New Finding
Modulation of the antitumor immune response by complement.
Markiewski MM, DeAngelis RA, …, Coukos G, Lambris JD
Nat Immunol
2008 Nov
9
(11):1225-35 [
abstract on PubMed
] [
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full text
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Selected by
| Alberto Mantovani
Evaluated 5 Jan 2009
6
Exceptional
F1000 Factor
9.0
New Finding
Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero.
Mold JE, Michaëlsson J, …, Nixon DF, McCune JM
Science
2008 Dec 5
322
(5907):1562-5 [
abstract on PubMed
] [
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Selected by
| Torben Lund
Evaluated 2 Jan 2009
7
Must Read
F1000 Factor
6.5
Confirmation
New Finding
Tech Advance
Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity.
Hildner K, Edelson BT, …, Murphy TL, Murphy KM
Science
2008 Nov 14
322
(5904):1097-100 [
abstract on PubMed
] [
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full text
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Selected by
| Adolfo Garcia-Sastre / Peter Van Endert
/ Ronald Germain with Wolfgang Kastenmueller
First evaluation 8 Dec 2008 | Latest evaluation 2 Jan 2009
8
Exceptional
F1000 Factor
8.0
Hypothesis
New Finding
Tech Advance
Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif.
Xu C, Gagnon E, …, Chou JJ, Wucherpfennig KW
Cell
2008 Nov 14
135
(4):702-13 [
abstract on PubMed
] [
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Selected by
| Brigitte Huber / Nick Gascoigne
First evaluation 24 Nov 2008 | Latest evaluation 9 Dec 2008
9
Must Read
F1000 Factor
6.5
Hypothesis
New Finding
Controversial
Memory CD8 T-cell compartment grows in size with immunological experience.
Vezys V, Yates A, …, Antia R, Masopust D
Nature
2008 Nov 12 [
abstract on PubMed
] [
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full text
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Selected by
| Barry Rouse / Michael McChesney / David Woodland
First evaluation 18 Nov 2008 | Latest evaluation 26 Nov 2008
10
Recommended
F1000 Factor
3.0
New Finding
Tech Advance
Migratory dermal dendritic cells act as rapid sensors of protozoan parasites.
Ng LG, Hsu A, …, Scott P, Weninger W
PLoS Pathog
2008 Nov
4
(11):e1000222 [
abstract on PubMed
] [
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FREE full text
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Selected by
| P'ng Loke
Evaluated 2 Jan 2009
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Novel Drug Target
Hypothesis
Confirmation
Controversial