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Control of Gene Expression
Nuclear Structure & Function


 MOST VIEWED PAPERS | Molecular Biology | calculated on 7 January 2009
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1
Exceptional
F1000 Factor 10.2

Hypothesis
New Finding
Tech Advance
Controversial
Novel Drug Target
 Efficient tumour formation by single human melanoma cells.
Quintana E, Shackleton M, …, Johnson TM, Morrison SJ
Nature 2008 Dec 4 456(7222):593-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ze'ev Ronai / Ruth Roberts / Dafna Bar-Sagi with Elda Grabocka / John Lazo
First evaluation 9 Dec 2008 | Latest evaluation 7 Jan 2009

 
2
Must Read
F1000 Factor 6.0

Tech Advance
 Protection of DNA during preparative agarose gel electrophoresis against damage induced by ultraviolet light.
Gründemann D, Schömig E
Biotechniques 1996 Nov 21:898-903 [abstract on PubMed] [related articles] [order article]
Selected by | Matthew Sachs
Evaluated 16 Dec 2008
 
3
Exceptional
F1000 Factor 10.7

Hypothesis
New Finding
Controversial
 Species-specific transcription in mice carrying human chromosome 21.
Wilson MD, Barbosa-Morais NL, …, Tavaré S, Odom DT
Science 2008 Oct 17 322(5900):434-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yoav Gilad / Kenneth Zaret / Deyou Zheng / Julin Maloof with Jose M. Jimenez-Gomez / Lin Chen with Reza Kalhor / Tom Misteli with Evi Soutoglou / Heng Zhu
First evaluation 13 Oct 2008 | Latest evaluation 23 Dec 2008
 
4
Exceptional
F1000 Factor 10.3

Hypothesis
New Finding
Novel Drug Target
 Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.
Pearce MJ, Mintseris J, …, Gygi SP, Darwin KH
Science 2008 Nov 14 322(5904):1104-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Virginia Miller / Tom Rapoport with Ann Marie Stanley / Zhen-Qiang Pan with Antonio Sarikas / Dieter Wolf / Raphael Valdivia
First evaluation 16 Oct 2008 | Latest evaluation 2 Jan 2009
 
5
Exceptional
F1000 Factor 11.7

Confirmation
Hypothesis
New Finding
 Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
Shi Y, Lan F, …, Casero RA, Shi Y
Cell 2004 Dec 29 119(7):941-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven Henikoff / Thomas Jenuwein / Chris Sander / Winship Herr / Dinah Singer / Robert Dutnall / Eric Selker / Frank Lyko / Daniel Reines / Benoit Coulombe / Robin Allshire
First evaluation 21 Dec 2004 | Latest evaluation 3 Feb 2005
 
6
Exceptional
F1000 Factor 12.8

Hypothesis
New Finding
 Control of gene expression by a natural metabolite-responsive ribozyme.
Winkler WC, Nahvi A, …, Collins JA, Breaker RR
Nature 2004 Mar 18 428(6980):281-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David M.J. Lilley / Richard Maraia / Samuel Butcher / Eric Westhof / Peter Unrau / Scott K. Silverman / Fritz Eckstein / Burckhard Seelig / Andrew D. Sharrocks / Janet Morrow / Andres Jaschke / John Burke / Reinhard Luehrmann
First evaluation 18 Mar 2004 | Latest evaluation 17 May 2004
 
7
Exceptional
F1000 Factor 9.2

Hypothesis
New Finding
 Switching from repression to activation: microRNAs can up-regulate translation.
Vasudevan S, Tong Y, Steitz JA
Science 2007 Dec 21 318(5858):1931-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Oliver Hobert / Rivka Dikstein / Lynne Maquat / Roy Long / Laura Johnston / Peter Sarnow / Michael Kiebler / Daniel Gallie / Nicola Gray
First evaluation 12 Dec 2007 | Latest evaluation 27 Mar 2008
 
8
Recommended
F1000 Factor 3.2

Hypothesis
New Finding
 MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.
Tay Y, Zhang J, …, Lim B, Rigoutsos I
Nature 2008 Oct 23 455(7216):1124-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yi Eve Sun with Weihong Ge / Peter Sarnow with Cara Pager
First evaluation 25 Nov 2008 | Latest evaluation 27 Nov 2008
 
9
Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory system.
Hogan DJ, Riordan DP, …, Herschlag D, Brown PO
PLoS Biol 2008 Oct 28 6(10):e255 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jeff Coller with Wenqian Hu
Evaluated 16 Dec 2008
 
10
Exceptional
F1000 Factor 9.0

New Finding
 Identification of Holliday junction resolvases from humans and yeast.
Ip SC, Rass U, …, Skehel JM, West SC
Nature 2008 Nov 20 456(7220):357-61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Junjie Chen
Evaluated 4 Dec 2008

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