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 MOST VIEWED PAPERS | Genomics & Genetics | calculated on 7 January 2009
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1
Exceptional
F1000 Factor 10.2

Hypothesis
New Finding
Tech Advance
Controversial
Novel Drug Target
Efficient tumour formation by single human melanoma cells.
Quintana E, Shackleton M, …, Johnson TM, Morrison SJ
Nature 2008 Dec 4 456(7222):593-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ze'ev Ronai / Ruth Roberts / Dafna Bar-Sagi with Elda Grabocka / John Lazo
First evaluation 9 Dec 2008 | Latest evaluation 7 Jan 2009

 
2
Must Read
F1000 Factor 6.0

Tech Advance
Rapid SNP discovery and genetic mapping using sequenced RAD markers.
Baird NA, Etter PD, …, Cresko WA, Johnson EA
PLoS ONE 2008 3(10):e3376 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tony Long
Evaluated 23 Dec 2008
 
3
Must Read
F1000 Factor 6.0

Tech Advance
Protection of DNA during preparative agarose gel electrophoresis against damage induced by ultraviolet light.
Gründemann D, Schömig E
Biotechniques 1996 Nov 21:898-903 [abstract on PubMed] [related articles] [order article]
Selected by | Matthew Sachs
Evaluated 16 Dec 2008
 
4
Must Read
F1000 Factor 6.0

Confirmation
Tech Advance
High-resolution mapping of copy-number alterations with massively parallel sequencing.
Chiang DY, Getz G, …, Meyerson M, Lander ES
Nat Methods 2008 Nov 30 [abstract on PubMed] [related articles] [full text]
Selected by | Pui-Yan Kwok
Evaluated 2 Jan 2009
 
5
Exceptional
F1000 Factor 14.5

Hypothesis
New Finding
Controversial
Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis.
Lolle SJ, Victor JL, Young JM, Pruitt RE
Nature 2005 Mar 24 434(7032):505-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Frank Lyko / Shigeru Iida / Kay Schneitz / Judy Wall / Marjori Matzke / James Carrington / Jose Luis Riechmann / Christian Hardtke / John Bowman / James Hu / Caren Chang / Venkatesan Sundaresan / Philip Benfey / Stephan Beck / Magnus Nordborg / Neelima Sinha / Martin Parniske / Elena Alvarez-Buylla / Elizabeth Kellogg / Elizabeth Hood
Dissenters | Alejandro Sanchez-Alvarado
First evaluation 24 Mar 2005 | Latest evaluation 24 May 2005

 
6
Exceptional
F1000 Factor 10.7

Hypothesis
New Finding
Controversial
Species-specific transcription in mice carrying human chromosome 21.
Wilson MD, Barbosa-Morais NL, …, Tavaré S, Odom DT
Science 2008 Oct 17 322(5900):434-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yoav Gilad / Kenneth Zaret / Deyou Zheng / Julin Maloof with Jose M. Jimenez-Gomez / Lin Chen with Reza Kalhor / Tom Misteli with Evi Soutoglou / Heng Zhu
First evaluation 13 Oct 2008 | Latest evaluation 23 Dec 2008
 
7
Must Read
F1000 Factor 6.0

New Finding
An epigenetic role for maternally inherited piRNAs in transposon silencing.
Brennecke J, Malone CD, …, Stark A, Hannon GJ
Science 2008 Nov 28 322(5906):1387-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Pamela Geyer
Evaluated 6 Jan 2009
 
8
Exceptional
F1000 Factor 10.3

Hypothesis
New Finding
Novel Drug Target
Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.
Pearce MJ, Mintseris J, …, Gygi SP, Darwin KH
Science 2008 Nov 14 322(5904):1104-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Virginia Miller / Tom Rapoport with Ann Marie Stanley / Zhen-Qiang Pan with Antonio Sarikas / Dieter Wolf / Raphael Valdivia
First evaluation 16 Oct 2008 | Latest evaluation 2 Jan 2009
 
9
Recommended
F1000 Factor 3.0

Hypothesis
New Finding
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes.
Epsztejn-Litman S, Feldman N, …, Cedar H, Bergman Y
Nat Struct Mol Biol 2008 Nov 15(11):1176-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wolf Reik with Miguel Branco
Evaluated 22 Dec 2008
 
10
Recommended
F1000 Factor 3.0

New Finding
Statistical tests between competing hypotheses of Hox cluster evolution.
Lanfear R, Bromham L
Syst Biol 2008 Oct 57(5):708-18 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rafael Zardoya with Diego San Mauro
Evaluated 18 Dec 2008

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