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Animal Genetics
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Biomacromolecule-Ligand Interactions
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Structure: RNA
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 MOST VIEWED PAPERS | Bioinformatics | calculated on 7 January 2009
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1
Exceptional
F1000 Factor 10.2

Hypothesis
New Finding
Tech Advance
Controversial
Novel Drug Target
 Efficient tumour formation by single human melanoma cells.
Quintana E, Shackleton M, …, Johnson TM, Morrison SJ
Nature 2008 Dec 4 456(7222):593-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ze'ev Ronai / Ruth Roberts / Dafna Bar-Sagi with Elda Grabocka / John Lazo
First evaluation 9 Dec 2008 | Latest evaluation 7 Jan 2009

 
2
Must Read
F1000 Factor 6.0

Tech Advance
 Rapid SNP discovery and genetic mapping using sequenced RAD markers.
Baird NA, Etter PD, …, Cresko WA, Johnson EA
PLoS ONE 2008 3(10):e3376 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tony Long
Evaluated 23 Dec 2008
 
3
Exceptional
F1000 Factor 9.0

Controversial
 Protein dynamical transition does not require protein structure.
He Y, Ku PI, …, Chen JY, Markelz AG
Phys Rev Lett 2008 Oct 24 101(17):178103 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Gruebele with Dr. Simon Ebbinghaus
Evaluated 22 Dec 2008
 
4
Must Read
F1000 Factor 6.4

Confirmation
New Finding
Tech Advance
 Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax.
Lovell JF, Billen LP, …, Leber B, Andrews DW
Cell 2008 Dec 12 135(6):1074-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Colman with W. Douglas Fairlie / Douglas Green with Jerry E. Chipuk
First evaluation 19 Dec 2008 | Latest evaluation 23 Dec 2008
 
5
Must Read
F1000 Factor 6.0

Confirmation
Tech Advance
 High-resolution mapping of copy-number alterations with massively parallel sequencing.
Chiang DY, Getz G, …, Meyerson M, Lander ES
Nat Methods 2008 Nov 30 [abstract on PubMed] [related articles] [full text]
Selected by | Pui-Yan Kwok
Evaluated 2 Jan 2009
 
6
Exceptional
F1000 Factor 14.5

Hypothesis
New Finding
Controversial
 Genome-wide non-mendelian inheritance of extra-genomic information in Arabidopsis.
Lolle SJ, Victor JL, Young JM, Pruitt RE
Nature 2005 Mar 24 434(7032):505-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Frank Lyko / Shigeru Iida / Kay Schneitz / Judy Wall / Marjori Matzke / James Carrington / Jose Luis Riechmann / Christian Hardtke / John Bowman / James Hu / Caren Chang / Venkatesan Sundaresan / Philip Benfey / Stephan Beck / Magnus Nordborg / Neelima Sinha / Martin Parniske / Elena Alvarez-Buylla / Elizabeth Kellogg / Elizabeth Hood
Dissenters | Alejandro Sanchez-Alvarado
First evaluation 24 Mar 2005 | Latest evaluation 24 May 2005

 
7
Recommended
F1000 Factor 3.0

Tech Advance
 The better tag remains unseen.
Durst FG, Ou HD, …, Dötsch V, Straub WE
J Am Chem Soc 2008 Nov 12 130(45):14932-3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Linda Ball with Victoria A. Higman
Evaluated 5 Dec 2008
 
8
Exceptional
F1000 Factor 10.7

Hypothesis
New Finding
Controversial
 Species-specific transcription in mice carrying human chromosome 21.
Wilson MD, Barbosa-Morais NL, …, Tavaré S, Odom DT
Science 2008 Oct 17 322(5900):434-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yoav Gilad / Kenneth Zaret / Deyou Zheng / Julin Maloof with Jose M. Jimenez-Gomez / Lin Chen with Reza Kalhor / Tom Misteli with Evi Soutoglou / Heng Zhu
First evaluation 13 Oct 2008 | Latest evaluation 23 Dec 2008
 
9
Exceptional
F1000 Factor 8.0

Hypothesis
New Finding
Tech Advance
 Bleach activates a redox-regulated chaperone by oxidative protein unfolding.
Winter J, Ilbert M, …, Ozcelik D, Jakob U
Cell 2008 Nov 14 135(4):691-701 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philip Burcham / Bruce Demple
Evaluated 8 Dec 2008
 
10
Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
 Nature, nurture, or chance: stochastic gene expression and its consequences.
Raj A, van Oudenaarden A
Cell 2008 Oct 17 135(2):216-26 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ram Samudrala with Jeremy Horst
Evaluated 2 Dec 2008

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