Faculty of 1000 Biology | Current Top 10

9-May-2008

Top 10s

ALL OF BIOLOGY

Current Top 10

All Time Top 10

Most-viewed Top 10

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	Exceptional
F1000 Factor 9.8

Hypothesis

New Finding

Tech Advance

Surface mobility of postsynaptic AMPARs tunes synaptic transmission.
Heine M, Groc L, …, Cognet L, Choquet D
Science 2008 Apr 11 320(5873):201-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Michael Andresen / Stuart Cull-Candy / Bettina Winckler

First evaluation 24 Apr 2008 | Latest evaluation 8 May 2008

	Exceptional
F1000 Factor 9.6

Confirmation

Hypothesis

New Finding

Rapid leukocyte migration by integrin-independent flowing and squeezing.
Lämmermann T, Bader BL, …, Fässler R, Sixt M
Nature 2008 May 1 453(7191):51-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Friedemann Kiefer

/ Kenneth Yamada

First evaluation 6 May 2008 | Latest evaluation 9 May 2008

	Exceptional
F1000 Factor 9.6

New Finding

Tech Advance

Novel Drug Target

The chemical genomic portrait of yeast: uncovering a phenotype for all genes.
Hillenmeyer ME, Fung E, …, Nislow C, Giaever G
Science 2008 Apr 18 320(5874):362-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Manyuan Long / Ramon Serrano

First evaluation 30 Apr 2008 | Latest evaluation 8 May 2008

	Exceptional
F1000 Factor 9.6

Hypothesis

New Finding

Tech Advance

Novel Drug Target

Reconstitution of pilus assembly reveals a bacterial outer membrane catalyst.
Nishiyama M, Ishikawa T, Rechsteiner H, Glockshuber R
Science 2008 Apr 18 320(5874):376-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Rino Rappuoli / Esther Bullitt
First evaluation 24 Apr 2008 | Latest evaluation 29 Apr 2008

	Exceptional
F1000 Factor 8.4

Confirmation

Hypothesis

New Finding

Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.
Wu X, Tu X, …, Williams DA, Long F
Cell 2008 Apr 18 133(2):340-53 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Chaya Kalcheim / Filippo Giancotti / Gregory Dressler

/ John Wallingford

First evaluation 22 Apr 2008 | Latest evaluation 6 May 2008

	Exceptional
F1000 Factor 8.1

Confirmation

New Finding

Novel Drug Target

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.
Dawlaty MM, Malureanu L, …, Grosschedl R, van Deursen JM
Cell 2008 Apr 4 133(1):103-15 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | David Wotton / Paul Clarke / Titia Sixma
First evaluation 18 Apr 2008 | Latest evaluation 28 Apr 2008

	Exceptional
F1000 Factor 8.0

New Finding

Novel Drug Target

An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models.
Burdelya LG, Krivokrysenko VI, …, Feinstein E, Gudkov AV
Science 2008 Apr 11 320(5873):226-30 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Alan Landay / Jenny Ting

First evaluation 25 Apr 2008 | Latest evaluation 8 May 2008

	Exceptional
F1000 Factor 8.0

New Finding

Following translation by single ribosomes one codon at a time.
Wen JD, Lancaster L, …, Bustamante C, Tinoco I
Nature 2008 Apr 3 452(7187):598-603 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Jose Valpuesta / Miles Wilkinson

First evaluation 29 Apr 2008 | Latest evaluation 2 May 2008

	Exceptional
F1000 Factor 8.0

Hypothesis

New Finding

Novel Drug Target

A nuclear receptor-like pathway regulating multidrug resistance in fungi.
Thakur JK, Arthanari H, …, Wagner G, Näär AM
Nature 2008 Apr 3 452(7187):604-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Guilhem Janbon / Paul Webb
First evaluation 18 Apr 2008 | Latest evaluation 30 Apr 2008

	Exceptional
F1000 Factor 8.0

Hypothesis

New Finding

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans.
Tullet JM, Hertweck M, …, Baumeister R, Blackwell TK
Cell 2008 Mar 21 132(6):1025-38 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Susan Mango / David Gems
First evaluation 15 Apr 2008 | Latest evaluation 28 Apr 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.