Faculty of 1000 Biology | All Time Top 10

7-Jan-2009

Top 10s

Neuroscience

Current Top 10

All Time Top 10

Most-viewed Top 10

Hidden Jewels Top 10

Sections Covered

Behavioural Neuroscience

Cognitive Neuroscience

Motor Systems

Neurobiology of Disease & Regeneration

Neurodevelopment

Neuronal & Glial Cell Biology

Neuronal Signalling Mechanisms

Sensory Systems

Theoretical Neuroscience

Related Sections

Neural Homeostasis

Neuropharmacology & Psychopharmacology

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	Exceptional
F1000 Factor 12.3

New Finding

Tech Advance

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system.
Livet J, Weissman TA, …, Sanes JR, Lichtman JW
Nature 2007 Nov 1 450(7166):56-62 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kees Jalink / Alain Ghysen / Jonathan Sweedler / Liqun Luo / Catherine Krull / Markus Ruegg / Stanley Appel / David P. Wolfer / Andy Groves / Bruce Cumming / Guoping Feng / Edvard I. Moser / Etienne Joly / Martine Roussel
First evaluation 8 Nov 2007 | Latest evaluation 22 Jan 2008

	Exceptional
F1000 Factor 11.3

Hypothesis

New Finding

Tech Advance

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Rasmussen SG, Choi HJ, …, Weis WI, Kobilka BK
Nature 2007 Nov 15 450(7168):383-7 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Leonardo Pardo / Fred Dyda / Carmen Dessauer / Arthur Christopoulos / Patricia C. Weber / Ian Hall / Marc Caron / Stephan Nussberger
First evaluation 30 Oct 2007 | Latest evaluation 3 Mar 2008

	Exceptional
F1000 Factor 11.2

Confirmation

New Finding

Tech Advance

Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex.
Ohki K, Chung S, …, Kara P, Reid RC
Nature 2005 Feb 10 433(7026):597-603 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kevan A. Martin / Matteo Carandini / Silvia Arber / Pamela Reinagel / Rafael Malach / Edvard I. Moser / Dora Angelaki / Bruce Cumming
First evaluation 28 Jan 2005 | Latest evaluation 20 Jun 2006

	Exceptional
F1000 Factor 11.1

Confirmation

New Finding

Tech Advance

STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis.
Willig KI, Rizzoli SO, …, Jahn R, Hell SW
Nature 2006 Apr 13 440(7086):935-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Lennart Brodin / David Stephens / Berl R. Oakley / Volker Haucke / Manfred Schliwa / Peter McPherson / Josep Rizo / Karolin Luger / Michael Kiebler
First evaluation 19 Apr 2006 | Latest evaluation 10 Apr 2007

	Exceptional
F1000 Factor 11.1

New Finding

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
Feske S, Gwack Y, …, Daly M, Rao A
Nature 2006 May 11 441(7090):179-85 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Roger Hardie / Angus Nairn / Colin Taylor / Tullio Pozzan / Andy Chan / Steve Ward / Anthony DeFranco / Dan Conrad
First evaluation 7 Apr 2006 | Latest evaluation 9 Jun 2006

	Exceptional
F1000 Factor 11.0

Confirmation

New Finding

Tech Advance

Novel Drug Target

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Cherezov V, Rosenbaum DM, …, Kobilka BK, Stevens RC
Science 2007 Nov 23 318(5854):1258-65 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Xiayang Qiu / Mark von Zastrow / Peter Artymiuk / Patricia C. Weber / Ram Samudrala / Petra Fromme / Marc Caron
First evaluation 31 Oct 2007 | Latest evaluation 10 Jan 2008

	Exceptional
F1000 Factor 11.0

Hypothesis

New Finding

Tech Advance

An RNA gene expressed during cortical development evolved rapidly in humans.
Pollard KS, Salama SR, …, Vanderhaeghen P, Haussler D
Nature 2006 Sep 14 443(7108):167-72 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Kevan A. Martin / John Abrams / Deyou Zheng / Andrew Feinberg / Rafael Zardoya / Ali H. Brivanlou / Robert Sapolsky / Gabriele Varani / Christopher A. Walsh
First evaluation 22 Aug 2006 | Latest evaluation 15 Mar 2007

	Exceptional
F1000 Factor 11.0

Hypothesis

New Finding

Controversial

TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells.
Corey DP, García-Añoveros J, …, Tamasauskas D, Zhang DS
Nature 2004 Dec 9 432(7018):723-30 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Roger Hardie / Karen P. Steel / Guy Richardson / Ardem Patapoutian / Peter Gillespie / Dora Angelaki / Ellen A. Lumpkin / Venkatesh Murthy
First evaluation 18 Oct 2004 | Latest evaluation 3 Dec 2004

	Exceptional
F1000 Factor 10.9

New Finding

Tech Advance

Multimodal fast optical interrogation of neural circuitry.
Zhang F, Wang LP, …, Gottschalk A, Deisseroth K
Nature 2007 Apr 5 446(7136):633-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Tullio Pozzan / Edvard I. Moser / Eileen Lafer / David P. Wolfer / Shai Shaham / Joel Elmquist / Ellen A. Lumpkin / Michael Kiebler
First evaluation 10 Apr 2007 | Latest evaluation 24 Jul 2007

	Exceptional
F1000 Factor 10.9

New Finding

Tech Advance

A photoactivatable GFP for selective photolabeling of proteins and cells.
Patterson GH, Lippincott-Schwartz J
Science 2002 Sep 13 297(5588):1873-7 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Ross Weatherman / Kermit Carraway / Colin Taylor / Karl Oparka / Volkhard Helms / W. Martin Usrey / Rachel Wong / Richard Maraia / Andrew Belmont
First evaluation 23 Sep 2002 | Latest evaluation 15 Nov 2002

All Time Top 10s are generated every day using papers added to F1000 Biology since the project started (Top 10s consider papers evaluated in the preceding month). Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.