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Cell Adhesion
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 TOP 10 | Cell Biology | calculated on 7 January 2009
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1
Exceptional
F1000 Factor 10.2

Hypothesis
New Finding
Tech Advance
Controversial
Novel Drug Target
 Efficient tumour formation by single human melanoma cells.
Quintana E, Shackleton M, …, Johnson TM, Morrison SJ
Nature 2008 Dec 4 456(7222):593-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ze'ev Ronai / Ruth Roberts / Dafna Bar-Sagi with Elda Grabocka / John Lazo
First evaluation 9 Dec 2008 | Latest evaluation 7 Jan 2009

 
2
Exceptional
F1000 Factor 8.3

Hypothesis
New Finding
 A Role for the ESCRT System in Cell Division in Archaea.
Samson RY, Obita T, …, Williams RL, Bell SD
Science 2008 Nov 13 [abstract on PubMed] [related articles] [full text]
Selected by | Linda Amos / Harold Erickson / Mohan Balasubramanian with Ramanujam Srinivasan and Mithilesh Mishra / Tom Stevens with Emily M. Coonrod
First evaluation 17 Nov 2008 | Latest evaluation 18 Dec 2008
 
3
Must Read
F1000 Factor 6.6

Confirmation
Hypothesis
New Finding
Controversial
 The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.
Nilsson J, Yekezare M, Minshull J, Pines J
Nat Cell Biol 2008 Dec 10(12):1411-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kevin Hardwick / Domenico Grieco / Silke Hauf
First evaluation 20 Nov 2008 | Latest evaluation 11 Dec 2008
 
4
Must Read
F1000 Factor 6.4

Confirmation
New Finding
Tech Advance
 Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax.
Lovell JF, Billen LP, …, Leber B, Andrews DW
Cell 2008 Dec 12 135(6):1074-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Colman with W. Douglas Fairlie / Douglas Green with Jerry E. Chipuk
First evaluation 19 Dec 2008 | Latest evaluation 23 Dec 2008
 
5
Must Read
F1000 Factor 6.4

Confirmation
Hypothesis
New Finding
 Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of hec1.
Guimaraes GJ, Dong Y, McEwen BF, Deluca JG
Curr Biol 2008 Nov 25 18(22):1778-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Silke Hauf / Linda Amos
First evaluation 12 Dec 2008 | Latest evaluation 17 Dec 2008
 
6
Must Read
F1000 Factor 4.8

Confirmation
Hypothesis
New Finding
 Kinetochore Attachments Require an Interaction between Unstructured Tails on Microtubules and Ndc80(Hec1).
Miller SA, Johnson ML, Stukenberg PT
Curr Biol 2008 Nov 25 18(22):1785-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Silke Hauf / Linda Amos
First evaluation 12 Dec 2008 | Latest evaluation 17 Dec 2008
 
7
Must Read
F1000 Factor 4.8

Hypothesis
New Finding
Novel Drug Target
 Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin.
Byres E, Paton AW, …, Rossjohn J, Beddoe T
Nature 2008 Dec 4 456(7222):648-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dave Bundle / Bruno Goud with Winfried Römer
First evaluation 8 Dec 2008 | Latest evaluation 16 Dec 2008
 
8
Must Read
F1000 Factor 4.8

Hypothesis
New Finding
 Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.
Narendra D, Tanaka A, Suen DF, Youle RJ
J Cell Biol 2008 Dec 1 183(5):795-803 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kenneth Downing with Alison Killilea / Robert Parton
First evaluation 9 Dec 2008 | Latest evaluation 16 Dec 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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