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 TOP 10 | Developmental Biology | calculated on 7 September 2008
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1
Exceptional
F1000 Factor 8.5

Confirmation
Hypothesis
New Finding
Centrosome Dysfunction in Drosophila Neural Stem Cells Causes Tumors that Are Not due to Genome Instability.
Castellanos E, Dominguez P, Gonzalez C
Curr Biol 2008 Jul 23 [abstract on PubMed] [related articles] [full text]
Selected by | Sharad Kumar / Anna Akhmanova / Yukiko Yamashita / Kristin White / Marcos Gonzalez-Gaitan
First evaluation 31 Jul 2008 | Latest evaluation 14 Aug 2008
 
2
Exceptional
F1000 Factor 8.3

Hypothesis
New Finding
A mechanism for asymmetric segregation of age during yeast budding.
Shcheprova Z, Baldi S, …, Gonnet G, Barral Y
Nature 2008 Aug 7 454(7205):728-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yukiko Yamashita / Thomas Nystrom / Audrey Gasch / Karsten Weis
First evaluation 7 Aug 2008 | Latest evaluation 4 Sep 2008
 
3
Exceptional
F1000 Factor 8.0

Hypothesis
New Finding
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.
Zhou Q, Brown J, …, Rajagopal J, Melton DA
Nature 2008 Aug 27 [abstract on PubMed] [related articles] [full text]
Selected by | Anthony Means / Phillip Newmark
First evaluation 4 Sep 2008 | Latest evaluation 5 Sep 2008
 
4
Exceptional
F1000 Factor 8.0

Hypothesis
New Finding
Novel Drug Target
An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C. elegans.
Budovskaya YV, Wu K, …, Johnson TE, Kim SK
Cell 2008 Jul 25 134(2):291-303 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nektarios Tavernarakis / Susan Mango
First evaluation 12 Aug 2008 | Latest evaluation 13 Aug 2008
 
5
Must Read
F1000 Factor 6.9

Hypothesis
New Finding
Four-jointed is a Golgi kinase that phosphorylates a subset of cadherin domains.
Ishikawa HO, Takeuchi H, Haltiwanger RS, Irvine KD
Science 2008 Jul 18 321(5887):401-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Filippo Giancotti / Norbert Perrimon / Valeri Vasioukhin / David Strutt / Heng Zhu with Hee Sool Rho
First evaluation 22 Jul 2008 | Latest evaluation 27 Aug 2008
 
6
Must Read
F1000 Factor 6.4

Confirmation
New Finding
Tech Advance
Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer.
Gubbels SP, Woessner DW, …, Ricci AJ, Brigande JV
Nature 2008 Aug 27 [abstract on PubMed] [related articles] [full text]
Selected by | Harukazu Nakamura / Andy Groves
Evaluated 4 Sep 2008
 
7
Must Read
F1000 Factor 6.4

Confirmation
New Finding
Tech Advance
Lensless high-resolution on-chip optofluidic microscopes for Caenorhabditis elegans and cell imaging.
Cui X, Lee LM, …, Psaltis D, Yang C
Proc Natl Acad Sci U S A 2008 Jul 28 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Markus Engstler / Bob Goldstein
First evaluation 5 Aug 2008 | Latest evaluation 6 Aug 2008
 
8
Must Read
F1000 Factor 4.9

New Finding
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.
Taddei A, Giampietro C, …, Dimmeler S, Dejana E
Nat Cell Biol 2008 Aug 10(8):923-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dietmar Vestweber / Eric Beyer / Talila Volk
First evaluation 29 Jul 2008 | Latest evaluation 14 Aug 2008
 
9
Must Read
F1000 Factor 4.8

Hypothesis
New Finding
The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery.
Davis NM, Kurpios NA, …, Martin JF, Tabin CJ
Dev Cell 2008 Jul 15(1):134-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patrick Tam / Denis Duboule
First evaluation 1 Sep 2008 | Latest evaluation 2 Sep 2008
 
10
Must Read
F1000 Factor 4.8

Hypothesis
New Finding
Natural variation in Pristionchus pacificus insect pheromone attraction involves the protein kinase EGL-4.
Hong RL, Witte H, Sommer RJ
Proc Natl Acad Sci U S A 2008 Jun 3 105(22):7779-84 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Fitch / Artyom Kopp
First evaluation 29 Jul 2008 | Latest evaluation 1 Aug 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.


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