Faculty of 1000 Biology | Current Top 10

17-May-2008

Top 10s

ALL OF BIOLOGY

Current Top 10

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Most-viewed Top 10

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	Exceptional
F1000 Factor 10.0

Hypothesis

New Finding

Tech Advance

Surface mobility of postsynaptic AMPARs tunes synaptic transmission.
Heine M, Groc L, …, Cognet L, Choquet D
Science 2008 Apr 11 320(5873):201-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Michael Andresen / Stuart Cull-Candy / Bettina Winckler / Johannes Hell

First evaluation 24 Apr 2008 | Latest evaluation 12 May 2008

	Exceptional
F1000 Factor 9.9

Confirmation

Hypothesis

New Finding

Rapid leukocyte migration by integrin-independent flowing and squeezing.
Lämmermann T, Bader BL, …, Fässler R, Sixt M
Nature 2008 May 1 453(7191):51-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Friedemann Kiefer / Kenneth Yamada / Jens V. Stein

First evaluation 6 May 2008 | Latest evaluation 13 May 2008

	Exceptional
F1000 Factor 9.6

New Finding

Tech Advance

Novel Drug Target

The chemical genomic portrait of yeast: uncovering a phenotype for all genes.
Hillenmeyer ME, Fung E, …, Nislow C, Giaever G
Science 2008 Apr 18 320(5874):362-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Manyuan Long / Ramon Serrano
First evaluation 30 Apr 2008 | Latest evaluation 8 May 2008

	Exceptional
F1000 Factor 9.6

Hypothesis

New Finding

Tech Advance

Novel Drug Target

Reconstitution of pilus assembly reveals a bacterial outer membrane catalyst.
Nishiyama M, Ishikawa T, Rechsteiner H, Glockshuber R
Science 2008 Apr 18 320(5874):376-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Rino Rappuoli / Esther Bullitt
First evaluation 24 Apr 2008 | Latest evaluation 29 Apr 2008

	Exceptional
F1000 Factor 8.4

Confirmation

Hypothesis

New Finding

Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.
Wu X, Tu X, …, Williams DA, Long F
Cell 2008 Apr 18 133(2):340-53 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Chaya Kalcheim / Filippo Giancotti / Gregory Dressler / John Wallingford
First evaluation 22 Apr 2008 | Latest evaluation 6 May 2008

	Exceptional
F1000 Factor 8.2

Hypothesis

New Finding

CASK Functions as a Mg2+-independent neurexin kinase.
Mukherjee K, Sharma M, …, Südhof TC, Wahl MC
Cell 2008 Apr 18 133(2):328-39 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Carmen Dessauer / Stevan Hubbard

/ Michael Ehlers

First evaluation 9 May 2008 | Latest evaluation 15 May 2008

	Exceptional
F1000 Factor 8.2

Confirmation

Hypothesis

New Finding

Tech Advance

Spatial regulators for bacterial cell division self-organize into surface waves in vitro.
Loose M, Fischer-Friedrich E, …, Kruse K, Schwille P
Science 2008 May 9 320(5877):789-92 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Orion Weiner

/ Mark Rose

/ R. Dyche Mullins

First evaluation 12 May 2008 | Latest evaluation 15 May 2008

	Exceptional
F1000 Factor 8.0

New Finding

Tech Advance

Why fishing magnifies fluctuations in fish abundance.
Anderson CN, Hsieh CH, …, May RM, Sugihara G
Nature 2008 Apr 17 452(7189):835-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Jordi Bascompte / John Marra

First evaluation 21 Apr 2008 | Latest evaluation 13 May 2008

	Exceptional
F1000 Factor 8.0

Confirmation

New Finding

Tech Advance

Highly integrated single-base resolution maps of the epigenome in Arabidopsis.
Lister R, O'Malley RC, …, Millar AH, Ecker JR
Cell 2008 May 2 133(3):523-36 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Gregory Copenhaver / Alisdair Fernie

First evaluation 9 May 2008 | Latest evaluation 13 May 2008

	Exceptional
F1000 Factor 8.0

New Finding

Novel Drug Target

An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models.
Burdelya LG, Krivokrysenko VI, …, Feinstein E, Gudkov AV
Science 2008 Apr 11 320(5873):226-30 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Alan Landay / Jenny Ting
First evaluation 25 Apr 2008 | Latest evaluation 8 May 2008

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.