Your browser version may not work well with NCBI's Web applications. More information here...
1: Science. 2007 Jul 13;317(5835):215-9.
Related Articles, Links
Click here to read Click here to read Click here to read
Comment in:
Prefrontal regions orchestrate suppression of emotional memories via a two-phase process.

Depue BE, Curran T, Banich MT.

Department of Psychology, University of Colorado, Boulder, CO 80309, USA. depue@colorado.edu

Whether memories can be suppressed has been a controversial issue in psychology and cognitive neuroscience for decades. We found evidence that emotional memories are suppressed via two time-differentiated neural mechanisms: (i) an initial suppression by the right inferior frontal gyrus over regions supporting sensory components of the memory representation (visual cortex, thalamus), followed by (ii) right medial frontal gyrus control over regions supporting multimodal and emotional components of the memory representation (hippocampus, amygdala), both of which are influenced by fronto-polar regions. These results indicate that memory suppression does occur and, at least in nonpsychiatric populations, is under the control of prefrontal regions.

Publication Types:
PMID: 17626877 [PubMed - indexed for MEDLINE]