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1: J Clin Microbiol. 2007 Jun;45(6):2034-6. Epub 2007 Apr 4.
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Metallo-beta-lactamase or extended-spectrum beta-lactamase: a wolf in sheep's clothing.

Espedido BA, Thomas LC, Iredell JR.

Centre for Infectious Diseases and Microbiology, University of Sydney, Westmead Hospital, Westmead, NSW 2145, Australia.

Diagnostic algorithms in commonly used automated bacterial identification systems fail to reliably identify a metallo-beta-lactamase in the Enterobacteriaceae. Misidentification as an extended-spectrum beta-lactamase may result in inappropriate dismissal of drugs such as aztreonam in favor of carbapenems, which may in turn select for a highly carabapenem resistant phenotype.

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PMID: 17409217 [PubMed - indexed for MEDLINE]

PMCID: PMC1933081