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Detection and spread of Escherichia coli possessing the plasmid-borne carbapenemase KPC-2 in Brooklyn, New York.

Bratu S, Brooks S, Burney S, Kochar S, Gupta J, Landman D, Quale J.

State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA. sbratu@downstate.edu

A carbapenem-resistant isolate of Escherichia coli was identified that possessed a 23-kb plasmid encoding Klebsiella pneumoniae carbapenemase type 2 (KPC-2). A subsequent surveillance study involving hospitals in Brooklyn, New York, revealed that, among 1417 E. coli isolates, 7 isolates (from 3 hospitals) possessed bla(KPC-2). E. coli possessing KPC-2 is emerging in our region, and improved methods for detection are urgently needed.

Publication Types:
PMID: 17342651 [PubMed - indexed for MEDLINE]