Your browser version may not work well with NCBI's Web applications. More information here...
Related Articles, Links
Click here to read Click here to read Click here to read
A simple DNA-based translation system.

Garibotti AV, Liao S, Seeman NC.

Department of Chemistry, New York University, New York, New York 10003, USA.

We have used DNA double crossover (DX) molecules to produce a translation system that generates unique molecular products. The particular species of DX molecule used contains an even number of half-turns between crossover points, so there is a continuous strand on both sides of the molecule. One of these strands acts as the input strand containing the message, and a second strand acts as the product of translation. The crossover strands carry the "code" that connects the two sides of the molecule. This system is more robust, more extendable, and simpler than previous DNA-based translation systems that have been reported. It is designed to be useful in a variety of applications that utilize the concept of translating from one code to another.

Publication Types:
PMID: 17243754 [PubMed - indexed for MEDLINE]

PMCID: PMC2523266