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1: Science. 2006 Dec 8;314(5805):1583-5.
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Operation of a DNA robot arm inserted into a 2D DNA crystalline substrate.

Ding B, Seeman NC.

Department of Chemistry, New York University, New York, NY 10003, USA.

The success of nanorobotics requires the precise placement and subsequent operation of specific nanomechanical devices at particular locations. The structural programmability of DNA makes it a particularly attractive system for nanorobotics. We have developed a cassette that enables the placement of a robust, sequence-dependent DNA robot arm within a two-dimensional (2D) crystalline DNA array. The cassette contains the device, an attachment site, and a reporter of state. We used atomic force microscopy to demonstrate that the rotary device is fully functional after insertion. Thus, a nanomechanical device can operate within a fixed frame of reference.

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PMID: 17158323 [PubMed - indexed for MEDLINE]