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Recommended
F1000 Factor
3.0
New Finding
Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure.
Watanabe T, Takeda T, …, Shirasawa T, Otsu K
J Am Coll Cardiol
2008 Aug 26
52
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| Michael Frenneaux with Julian O M Ormerod
Evaluated 12 Nov 2008
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New Finding
TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis.
Wang H, Peters T, …, Weiss JM, Scharffetter-Kochanek K
J Clin Invest
2008 Jul
118
(7):2629-39 [
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| Mohamed Sayegh with Jessamyn Bagley
Evaluated 21 Oct 2008
Recommended
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3.0
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The Death Receptor 3-TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis.
Bull MJ, Williams AS, …, Al-Shamkhani A, Wang EC
J Exp Med
2008 Sep 29 [
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| Richard L. Stevens
Evaluated 10 Oct 2008
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3.0
New Finding
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Cathepsin B is involved in the trafficking of TNF-alpha-containing vesicles to the plasma membrane in macrophages.
Ha SD, Martins A, …, Chan BM, Kim SO
J Immunol
2008 Jul 1
181
(1):690-7 [
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Selected by
| Robert Booth
Evaluated 25 Sep 2008
Recommended
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3.0
Hypothesis
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Collagen Fibril Formation: A NEW TARGET TO LIMIT FIBROSIS.
Chung HJ, Steplewski A, …, Uitto J, Fertala A
J Biol Chem
2008 Sep 19
283
(38):25879-25886 [
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Selected by
| Jonathan Jones
Evaluated 22 Sep 2008
Recommended
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Antigen-specific apheresis of human anti-acetylcholine receptor autoantibodies from myasthenia gravis patients' sera using Escherichia coli-expressed receptor domains.
Zisimopoulou P, Lagoumintzis G, Poulas K, Tzartos SJ
J Neuroimmunol
2008 Aug 30
200
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Selected by
| Lin Chen
Evaluated 17 Sep 2008
Must Read
F1000 Factor
6.0
New Finding
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Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro.
Wang H, Yoshiko Y, …, Aubin JE, Maeda N
J Bone Miner Res
2008 Jun
23
(6):939-48 [
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Selected by
| Eleanor Lederer
Evaluated 3 Sep 2008
Recommended
F1000 Factor
3.0
New Finding
Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis.
Armand AS, Bourajjaj M, …, Redondo JM, De Windt LJ
J Biol Chem
2008 Aug 1 [
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Selected by
| Lin Chen
Evaluated 2 Sep 2008
Recommended
F1000 Factor
3.0
Hypothesis
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The initiation factor eIF3-f is a major target for atrogin1/MAFbx function in skeletal muscle atrophy.
Lagirand-Cantaloube J, Offner N, …, Segura CT, Leibovitch SA
EMBO J
2008 Apr 23
27
(8):1266-76 [
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Selected by
| Paul Greenhaff with Andrew Murton
Evaluated 2 Sep 2008
Recommended
F1000 Factor
3.0
Confirmation
New Finding
Trend in incidence of osteoporosis-related fractures among 40- to 69-year-old women: analysis of a large insurance claims database, 2000-2005.
Islam S, Liu Q, Chines A, Helzner E
Menopause
2008 Jul 25 [
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Selected by
| Henry Burger
Evaluated 21 Aug 2008
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