6-Jul-2009
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Exceptional
F1000 Factor
9.0
New Finding
Tech Advance
The establishment of gene silencing at single-cell resolution.
Osborne EA, Dudoit S, Rine J
Nat Genet
2009 Jul
41
(7):800-6 [
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Selected by
| Fyodor Urnov
Evaluated 2 Jul 2009
Exceptional
F1000 Factor
9.0
New Finding
Tech Advance
Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.
Ohya T, Miaczynska M, …, Kalaidzidis Y, Zerial M
Nature
2009 Jun 25
459
(7250):1091-7 [
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Selected by
| Josep Rizo
Evaluated 30 Jun 2009
Must Read
F1000 Factor
6.0
New Finding
Structural mechanism of substrate RNA recruitment in H/ACA RNA-guided pseudouridine synthase.
Duan J, Li L, …, Wang W, Ye K
Mol Cell
2009 May 14
34
(4):427-39 [
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Selected by
| Eric Westhof
Evaluated 29 Jun 2009
Recommended
F1000 Factor
3.0
New Finding
Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab.
Aoki ST, Settembre EC, …, Harrison SC, Dormitzer PR
Science
2009 Jun 12
324
(5933):1444-7 [
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Selected by
| James Crowe
Evaluated 26 Jun 2009
Recommended
F1000 Factor
3.0
Hypothesis
An unfolded CH1 domain controls the assembly and secretion of IgG antibodies.
Feige MJ, Groscurth S, …, Hendershot LM, Buchner J
Mol Cell
2009 Jun 12
34
(5):569-79 [
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Selected by
| Robert Kelley
Evaluated 26 Jun 2009
Must Read
F1000 Factor
6.0
New Finding
Structural basis for DNA binding by replication initiator Mcm10.
Warren EM, Vaithiyalingam S, …, Chazin WJ, Eichman BF
Structure
2008 Dec 10
16
(12):1892-901 [
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Selected by
| Sylvie Doublie
Evaluated 26 Jun 2009
Must Read
F1000 Factor
6.0
Confirmation
Hypothesis
New Finding
Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor.
Dienstbier M, Boehl F, Li X, Bullock SL
Genes Dev
2009 Jun 10 [
abstract on PubMed
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Selected by
| Anna Akhmanova
Evaluated 26 Jun 2009
Recommended
F1000 Factor
3.0
Confirmation
New Finding
Role of kinesin-1 and cytoplasmic dynein in endoplasmic reticulum movement in VERO cells.
Wozniak MJ, Bola B, …, Levakova V, Allan VJ
J Cell Sci
2009 Jun 15
122
(Pt 12):1979-89 [
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Selected by
| Anna Akhmanova
Evaluated 26 Jun 2009
Recommended
F1000 Factor
3.0
Hypothesis
The Core Signaling Proteins of Bacterial Chemotaxis Assemble To Form an Ultrastable Complex.
Erbse AH, Falke JJ
Biochemistry
2009 Jun 15 [
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Selected by
| George Ordal
Evaluated 25 Jun 2009
Must Read
F1000 Factor
6.0
New Finding
Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base.
Funakoshi M, Tomko RJ, Kobayashi H, Hochstrasser M
Cell
2009 May 29
137
(5):887-99 [
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Selected by
| Michael Rape
Evaluated 24 Jun 2009
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