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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 TARP modulation of synaptic AMPA receptor trafficking and gating depends on multiple intracellular domains.
Milstein AD, Nicoll RA
Proc Natl Acad Sci U S A 2009 Jun 22 [abstract on PubMed] [related articles] [full text]
Selected by | Michael Ehlers
Evaluated 30 Jun 2009

Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
 Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.
Ohya T, Miaczynska M, …, Kalaidzidis Y, Zerial M
Nature 2009 Jun 25 459(7250):1091-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Josep Rizo
Evaluated 30 Jun 2009

Recommended
F1000 Factor 3.0

New Finding
 Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation .
Tsai SJ, Sen U, …, Bottini N, Chen XS
Biochemistry 2009 Jun 9 48(22):4838-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Amy Barrios
Evaluated 29 Jun 2009

Recommended
F1000 Factor 3.0

New Finding
 Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab.
Aoki ST, Settembre EC, …, Harrison SC, Dormitzer PR
Science 2009 Jun 12 324(5933):1444-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Crowe
Evaluated 26 Jun 2009

Recommended
F1000 Factor 3.0

New Finding
 Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells.
Diaz F, Gravotta D, …, Falck-Pedersen E, Rodriguez-Boulan E
Proc Natl Acad Sci U S A 2009 Jun 19 [abstract on PubMed] [related articles] [full text]
Selected by | Carolyn Coyne
Evaluated 26 Jun 2009

Recommended
F1000 Factor 3.0

Confirmation
Tech Advance
 Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2.
Hammond GR, Schiavo G, Irvine RF
Biochem J 2009 Jun 9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tamas Balla
Evaluated 26 Jun 2009

Must Read
F1000 Factor 6.0

Confirmation
Hypothesis
New Finding
 Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor.
Dienstbier M, Boehl F, Li X, Bullock SL
Genes Dev 2009 Jun 10 [abstract on PubMed] [related articles] [full text]
Selected by | Anna Akhmanova
Evaluated 26 Jun 2009

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Role of kinesin-1 and cytoplasmic dynein in endoplasmic reticulum movement in VERO cells.
Wozniak MJ, Bola B, …, Levakova V, Allan VJ
J Cell Sci 2009 Jun 15 122(Pt 12):1979-89 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anna Akhmanova
Evaluated 26 Jun 2009

Must Read
F1000 Factor 6.0

New Finding
 Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base.
Funakoshi M, Tomko RJ, Kobayashi H, Hochstrasser M
Cell 2009 May 29 137(5):887-99 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Rape
Evaluated 24 Jun 2009

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Synaptic vesicle recycling at CNS snapses without AP-2.
Kim SH, Ryan TA
J Neurosci 2009 Mar 25 29(12):3865-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter McPherson
Evaluated 24 Jun 2009


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