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Browse > Structural Biology > Structure: Replication & Repair
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Recommended
F1000 Factor 3.0

New Finding
 Phase resetting of the mammalian circadian clock by DNA damage.
Oklejewicz M, Destici E, …, Janssens R, van der Horst GT
Curr Biol 2008 Feb 26 18(4):286-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean Clairambault
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Human DNA polymerase iota protects cells against oxidative stress.
Petta TB, Nakajima S, …, Yasui A, Kannouche P
EMBO J 2008 Nov 5 27(21):2883-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Lehmann
Evaluated 13 Nov 2008

Must Read
F1000 Factor 6.6

Hypothesis
New Finding
 HARP is an ATP-driven annealing helicase.
Yusufzai T, Kadonaga JT
Science 2008 Oct 31 322(5902):748-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Botchan / Lucio Comai / Jessica Downs
First evaluation 13 Nov 2008 | Latest evaluation 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
 Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase.
Nagai S, Dubrana K, …, Gasser SM, Krogan NJ
Science 2008 Oct 24 322(5901):597-602 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Steven Brill
Evaluated 12 Nov 2008

Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
Tech Advance
 Global reorganization of replication domains during embryonic stem cell differentiation.
Hiratani I, Ryba T, …, Schübeler D, Gilbert DM
PLoS Biol 2008 Oct 7 6(10):e245 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joel Huberman
Evaluated 11 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.
Dimitrova N, Chen YC, Spector DL, de Lange T
Nature 2008 Oct 19 [abstract on PubMed] [related articles] [full text]
Selected by | Jiri Lukas
Evaluated 7 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 A model for transmission of the H3K27me3 epigenetic mark.
Hansen KH, Bracken AP, …, Lerdrup M, Helin K
Nat Cell Biol 2008 Nov 10:1291-300 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Leonie Ringrose
Evaluated 6 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response.
Morin I, Ngo HP, …, Morrice N, Lydall D
EMBO J 2008 Sep 17 27(18):2400-10 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lorraine Symington
Evaluated 4 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine.
Lee S, Bowman BR, …, Wang S, Verdine GL
J Am Chem Soc 2008 Sep 3 130(35):11570-1 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Stephen Woski
Evaluated 3 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 SbcCD causes a double-strand break at a DNA palindrome in the Escherichia coli chromosome.
Eykelenboom JK, Blackwood JK, Okely E, Leach DR
Mol Cell 2008 Mar 14 29(5):644-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Marinus
Evaluated 29 Oct 2008


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