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Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 Light enhanced amino acid uptake by dominant bacterioplankton groups in surface waters of the Atlantic Ocean.
Mary I, Tarran GA, …, Burkill PH, Zubkov MV
FEMS Microbiol Ecol 2008 Jan 63(1):36-45 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Hobbie with Hugh Ducklow
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
 Stimulation of Ebola virus production from persistent infection through activation of the Ras/MAPK pathway.
Strong JE, Wong G, …, Kobinger GP, Feldmann H
Proc Natl Acad Sci U S A 2008 Nov 3 105 [abstract on PubMed] [related articles] [full text]
Selected by | Kanta Subbarao with Catherine Luke
Evaluated 19 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs.
Hirota K, Miyoshi T, …, Shibata T, Ohta K
Nature 2008 Nov 6 456(7218):130-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Daniel Reines
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Controversial
 The transcriptional repressor protein NsrR senses nitric oxide directly via a [2Fe-2S] cluster.
Tucker NP, Hicks MG, …, Dixon R, Hutchings MI
PLoS ONE 2008 3(11):e3623 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephen Spiro
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Controversial
 Ubiquitylation of the COMPASS component Swd2 links H2B ubiquitylation to H3K4 trimethylation.
Vitaliano-Prunier A, Menant A, …, Gwizdek C, Dargemont C
Nat Cell Biol 2008 Nov 10(11):1365-71 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bernhard Dichtl with André Halbach
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Bacterial biosynthesis of a multipotent stilbene.
Joyce SA, Brachmann AO, …, Clarke DJ, Bode HB
Angew Chem Int Ed Engl 2008 47(10):1942-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Barrie Wilkinson
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 A small molecule enhances RNA interference and promotes microRNA processing.
Shan G, Li Y, …, He C, Jin P
Nat Biotechnol 2008 Aug 26(8):933-40 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gabriele Varani
Evaluated 14 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Splicing factors facilitate RNAi-directed silencing in fission yeast.
Bayne EH, Portoso M, …, Rappsilber J, Allshire RC
Science 2008 Oct 24 322(5901):602-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Craig Pikaard
Evaluated 13 Nov 2008

Must Read
F1000 Factor 6.5

Hypothesis
New Finding
 A unique cell division machinery in the Archaea.
Lindås AC, Karlsson EA, …, Ettema TJ, Bernander R
Proc Natl Acad Sci U S A 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | William Margolin / Linda Amos / Harold Erickson
First evaluation 13 Nov 2008 | Latest evaluation 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 Substituted 2-Imino-5-arylidenethiazolidin-4-one Inhibitors of Bacterial Type III Secretion.
Kline T, Felise HB, …, Nguyen HV, Miller SI
J Med Chem 2008 Oct 24 0 [abstract on PubMed] [related articles] [full text]
Selected by | Robert Fecik
Evaluated 13 Nov 2008


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