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Cellular Microbiology & Pathogenesis
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Must Read
F1000 Factor 6.0

New Finding
 Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells.
Kang SJ, Liang HE, Reizis B, Locksley RM
Immunity 2008 Nov 29(5):819-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jenny Ting
Evaluated 1 Dec 2008

Must Read
F1000 Factor 6.0

New Finding
 Antigen-mediated T cell expansion regulated by parallel pathways of death.
Ch'en IL, Beisner DR, …, Hoffmann A, Hedrick SM
Proc Natl Acad Sci U S A 2008 Nov 11 105(45):17463-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Astar Winoto
Evaluated 28 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells.
Bell BD, Leverrier S, …, Morrissette NS, Walsh CM
Proc Natl Acad Sci U S A 2008 Oct 28 105(43):16677-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Astar Winoto
Evaluated 28 Nov 2008

Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
 Eosinophil granules function extracellularly as receptor-mediated secretory organelles.
Neves JS, Perez SA, …, Moqbel R, Weller PF
Proc Natl Acad Sci U S A 2008 Nov 18 [abstract on PubMed] [related articles] [full text]
Selected by | Marc Rothenberg
Evaluated 27 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
Tech Advance
 Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3varepsilon Cytoplasmic Tyrosine-Based Motif.
Xu C, Gagnon E, …, Chou JJ, Wucherpfennig KW
Cell 2008 Nov 14 135(4):702-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Brigitte Huber
Evaluated 24 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Structure of IL-22 bound to its high-affinity IL-22R1 chain.
Jones BC, Logsdon NJ, Walter MR
Structure 2008 Sep 10 16(9):1333-44 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gideon Schreiber
Evaluated 20 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.
Yano M, Kuroda N, …, Mouri Y, Matsumoto M
J Exp Med 2008 Nov 17 [abstract on PubMed] [related articles] [full text]
Selected by | David Chaplin
Evaluated 19 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Glucose induces an autocrine activation of the Wnt/beta-catenin pathway in macrophage cell lines.
Anagnostou SH, Shepherd PR
Biochem J 2008 Dec 1 416(2):211-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alex Toker
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA.
Suzuki T, Sakagami T, …, van der Loo JC, Trapnell BC
J Exp Med 2008 Oct 27 [abstract on PubMed] [related articles] [full text]
Selected by | Glenn Dranoff
Evaluated 17 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
 CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming.
Martín-Fontecha A, Baumjohann D, …, Lanzavecchia A, Sallusto F
J Exp Med 2008 Oct 27 205(11):2561-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Linda Bradley
Evaluated 14 Nov 2008


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