29-Aug-2008
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Immunology
Leukocyte Develo...
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Must Read
F1000 Factor
6.0
Hypothesis
New Finding
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance.
Nedjic J, Aichinger M, …, Mizushima N, Klein L
Nature
2008 Aug 13 [
abstract on PubMed
] [
related articles
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full text
]
Selected by
| Vojo Deretic
Evaluated 27 Aug 2008
Recommended
F1000 Factor
3.0
Confirmation
Autoreactive marginal zone B cells are spontaneously activated but lymph node B cells require T cell help.
Mandik-Nayak L, Racz J, Sleckman BP, Allen PM
J Exp Med
2006 Aug 7
203
(8):1985-98 [
abstract on PubMed
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full text
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Selected by
| Antony Basten with Pablo Silveira
Evaluated 21 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution.
Hauri-Hohl MM, Zuklys S, …, Roes J, Holländer GA
Blood
2008 Aug 1
112
(3):626-34 [
abstract on PubMed
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full text
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Selected by
| Mohamed Sayegh with Jessamyn Bagley
Evaluated 20 Aug 2008
Recommended
F1000 Factor
3.0
Confirmation
New Finding
ADAMTS13: a new link between thrombosis and inflammation.
Chauhan AK, Kisucka J, …, Scheiflinger F, Wagner DD
J Exp Med
2008 Aug 11 [
abstract on PubMed
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Selected by
| William A Muller
Evaluated 19 Aug 2008
Must Read
F1000 Factor
6.4
New Finding
Deletional tolerance mediated by extrathymic Aire-expressing cells.
Gardner JM, Devoss JJ, …, Krummel MF, Anderson MS
Science
2008 Aug 8
321
(5890):843-7 [
abstract on PubMed
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Selected by
| Peter Van Endert / Torben Lund
First evaluation 18 Aug 2008 | Latest evaluation 19 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
Controversial
In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells.
Khayrullina T, Yen JH, Jing H, Ganea D
J Immunol
2008 Jul 1
181
(1):721-35 [
abstract on PubMed
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Selected by
| Klaus Ley
Evaluated 13 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages.
Nurieva RI, Chung Y, …, Tian Q, Dong C
Immunity
2008 Jul
29
(1):138-49 [
abstract on PubMed
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Selected by
| Toshinori Nakayama with Motoko Kimura
Evaluated 12 Aug 2008
Must Read
F1000 Factor
6.0
New Finding
Continuous engagement of a self-specific activation receptor induces NK cell tolerance.
Tripathy SK, Keyel PA, …, Schneeberger A, Yokoyama WM
J Exp Med
2008 Jul 7 [
abstract on PubMed
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full text
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Selected by
| Eric Vivier
Evaluated 7 Aug 2008
Must Read
F1000 Factor
6.0
New Finding
Tolerance of NK cells encountering their viral ligand during development.
Sun JC, Lanier LL
J Exp Med
2008 Jul 7 [
abstract on PubMed
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full text
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Selected by
| Eric Vivier
Evaluated 7 Aug 2008
Must Read
F1000 Factor
6.0
Confirmation
New Finding
Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.
Reynaud D, Demarco IA, …, Winandy S, Singh H
Nat Immunol
2008 Aug
9
(8):927-36 [
abstract on PubMed
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full text
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Selected by
| Pierre Ferrier
Evaluated 31 Jul 2008
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