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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Origins and evolution of eukaryotic RNA interference.
Shabalina SA, Koonin EV
Trends Ecol Evol 2008 Aug 18 [abstract on PubMed] [related articles] [full text]
Selected by | Marjori Matzke
Evaluated 5 Sep 2008


Recommended
F1000 Factor 3.0

Tech Advance
mirWIP: microRNA target prediction based on microRNA-containing ribonucleoprotein-enriched transcripts.
Hammell M, Long D, …, Ding Y, Ambros V
Nat Methods 2008 Aug 17 5 [abstract on PubMed] [related articles] [full text]
Selected by | Robert K Herman
Evaluated 5 Sep 2008

Must Read
F1000 Factor 6.0

Hypothesis
Controversial
Nanoscale organization of hedgehog is essential for long-range signaling.
Vyas N, Goswami D, …, Sowdhamini R, Mayor S
Cell 2008 Jun 27 133(7):1214-27 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Couchman
Evaluated 4 Sep 2008

Must Read
F1000 Factor 6.4

Confirmation
New Finding
Tech Advance
Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer.
Gubbels SP, Woessner DW, …, Ricci AJ, Brigande JV
Nature 2008 Aug 27 [abstract on PubMed] [related articles] [full text]
Selected by | Harukazu Nakamura / Andy Groves
Evaluated 4 Sep 2008

Exceptional
F1000 Factor 8.0

Hypothesis
New Finding
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.
Zhou Q, Brown J, …, Rajagopal J, Melton DA
Nature 2008 Aug 27 [abstract on PubMed] [related articles] [full text]
Selected by | Anthony Means / Phillip Newmark
First evaluation 4 Sep 2008 | Latest evaluation 5 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
Structural analysis of the recognition of the negative regulator NmrA and DNA by the zinc finger from the GATA-type transcription factor AreA.
Kotaka M, Johnson C, …, Ren J, Stammers DK
J Mol Biol 2008 Aug 29 381(2):373-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lin Chen
Evaluated 4 Sep 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Regulation of epithelial branching morphogenesis and cancer cell growth of the prostate by Wnt signaling.
Wang BE, Wang XD, …, Polakis P, Gao WQ
PLoS ONE 2008 3(5):e2186 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Arthur Mercurio
Evaluated 3 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis.
Armand AS, Bourajjaj M, …, Redondo JM, De Windt LJ
J Biol Chem 2008 Aug 1 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lin Chen
Evaluated 2 Sep 2008

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
New Finding
CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary disease.
Tsang WY, Bossard C, …, Malhotra V, Dynlacht BD
Dev Cell 2008 Aug 15(2):187-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anna Akhmanova
Evaluated 1 Sep 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
OSM-11 Facilitates LIN-12 Notch Signaling during Caenorhabditis elegans Vulval Development.
Komatsu H, Chao MY, …, Boxem M, Hart AC
PLoS Biol 2008 Aug 12 6(8):e196 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Helen Chamberlin
Evaluated 29 Aug 2008


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