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F1000 Factor 3.0

Tech Advance
The transition from differential equations to Boolean networks: a case study in simplifying a regulatory network model.
Davidich M, Bornholdt S
J Theor Biol 2008 Dec 7 255(3):269-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philip Maini
Evaluated 19 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Actin dynamics is essential for myosin-based transport of membrane organelles.
Semenova I, Burakov A, …, Kashina A, Rodionov V
Curr Biol 2008 Oct 28 18(20):1581-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anna Akhmanova
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.
Brown JM, Green J, …, Iborra FJ, Buckle VJ
J Cell Biol 2008 Sep 22 182(6):1083-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Shaw
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Glucose induces an autocrine activation of the Wnt/beta-catenin pathway in macrophage cell lines.
Anagnostou SH, Shepherd PR
Biochem J 2008 Dec 1 416(2):211-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alex Toker
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Structure-activity relationships study of bastadin 6, an anti-angiogenic brominated-tyrosine derived metabolite from marine sponge.
Kotoku N, Hiramatsu A, …, Aoki S, Kobayashi M
Arch Pharm (Weinheim) 2008 Sep 341(9):568-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tadeusz Molinski
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
A Role for the ESCRT System in Cell Division in Archaea.
Samson RY, Obita T, …, Williams RL, Bell SD
Science 2008 Nov 13 [abstract on PubMed] [related articles] [full text]
Selected by | Linda Amos
Evaluated 17 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Phase resetting of the mammalian circadian clock by DNA damage.
Oklejewicz M, Destici E, …, Janssens R, van der Horst GT
Curr Biol 2008 Feb 26 18(4):286-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jean Clairambault
Evaluated 14 Nov 2008

Must Read
F1000 Factor 6.0

New Finding
Novel Drug Target
Rac activation and inactivation control plasticity of tumor cell movement.
Sanz-Moreno V, Gadea G, …, Sahai E, Marshall CJ
Cell 2008 Oct 31 135(3):510-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Richard Klemke
Evaluated 13 Nov 2008

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F1000 Factor 3.0

New Finding
Human DNA polymerase iota protects cells against oxidative stress.
Petta TB, Nakajima S, …, Yasui A, Kannouche P
EMBO J 2008 Nov 5 27(21):2883-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alan Lehmann
Evaluated 13 Nov 2008

Must Read
F1000 Factor 6.5

Hypothesis
New Finding
A unique cell division machinery in the Archaea.
Lindås AC, Karlsson EA, …, Ettema TJ, Bernander R
Proc Natl Acad Sci U S A 2008 Nov 5 [abstract on PubMed] [related articles] [full text]
Selected by | William Margolin / Linda Amos / Harold Erickson
First evaluation 13 Nov 2008 | Latest evaluation 18 Nov 2008


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