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F1000 Factor 3.0

New Finding
Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts.
Weiger MC, Wang CC, …, Rhoden JJ, Haugh JM
J Cell Sci 2009 Feb 1 122(Pt 3):313-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Janetopoulos
Evaluated 2 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
Yurt, Coracle, Neurexin IV and the Na(+),K(+)-ATPase form a novel group of epithelial polarity proteins.
Laprise P, Lau KM, …, McGlade CJ, Tepass U
Nature 2009 Jun 25 459(7250):1141-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Bilder
Evaluated 30 Jun 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Nuclear transport factor directs localization of protein synthesis during mitosis.
van den Bogaart G, Meinema AC, …, Veenhoff LM, Poolman B
Nat Cell Biol 2009 Mar 11(3):350-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Timothy A. Bolger and Susan Wente
Evaluated 30 Jun 2009

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
The unitary event underlying multiquantal EPSCs at a hair cell's ribbon synapse.
Li GL, Keen E, …, Hudspeth AJ, von Gersdorff H
J Neurosci 2009 Jun 10 29(23):7558-68 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tobias Moser
Evaluated 30 Jun 2009

Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.
Ohya T, Miaczynska M, …, Kalaidzidis Y, Zerial M
Nature 2009 Jun 25 459(7250):1091-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Josep Rizo
Evaluated 30 Jun 2009

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
Endocytosis of MHC molecules by distinct membrane rafts.
Knorr R, Karacsonyi C, Lindner R
J Cell Sci 2009 May 15 122(Pt 10):1584-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul Roche
Evaluated 29 Jun 2009

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.
Singh AK, Riederer B, …, Hogema BM, Seidler U
J Clin Invest 2009 Mar 119(3):540-50 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ivana Novak
Evaluated 29 Jun 2009


Recommended
F1000 Factor 3.0

New Finding
Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab.
Aoki ST, Settembre EC, …, Harrison SC, Dormitzer PR
Science 2009 Jun 12 324(5933):1444-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | James Crowe
Evaluated 26 Jun 2009

Recommended
F1000 Factor 3.0

New Finding
Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells.
Diaz F, Gravotta D, …, Falck-Pedersen E, Rodriguez-Boulan E
Proc Natl Acad Sci U S A 2009 Jun 19 [abstract on PubMed] [related articles] [full text]
Selected by | Carolyn Coyne
Evaluated 26 Jun 2009

Recommended
F1000 Factor 3.0

Confirmation
Tech Advance
Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2.
Hammond GR, Schiavo G, Irvine RF
Biochem J 2009 Jun 9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tamas Balla
Evaluated 26 Jun 2009


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