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Control of Gene Expression
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Browse > Cell Biology > Control of Gene Expression
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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The histone variant H3.3 regulates gene expression during lytic infection by Herpes Simplex Virus, HSV-1.
Placek BJ, Huang J, …, Fraser NW, Berger SL
J Virol 2008 Nov 12 [abstract on PubMed] [related articles] [full text]
Selected by | Jim Smiley
Evaluated 21 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
Tech Advance
 Alternative isoform regulation in human tissue transcriptomes.
Wang ET, Sandberg R, …, Schroth GP, Burge CB
Nature 2008 Nov 2 [abstract on PubMed] [related articles] [full text]
Selected by | Ken Irvine with Yongqiang Feng
Evaluated 20 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.
Kanadia RN, Clark VE, …, Trimarchi JM, Cepko CL
Development 2008 Dec 135(23):3923-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Reinhard Luehrmann
Evaluated 20 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription.
Lefevre P, Witham J, …, Cockerill PN, Bonifer C
Mol Cell 2008 Oct 10 32(1):129-39 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rob White
Evaluated 19 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.
Yano M, Kuroda N, …, Mouri Y, Matsumoto M
J Exp Med 2008 Nov 17 [abstract on PubMed] [related articles] [full text]
Selected by | David Chaplin
Evaluated 19 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.
Brown JM, Green J, …, Iborra FJ, Buckle VJ
J Cell Biol 2008 Sep 22 182(6):1083-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Shaw
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Glucose induces an autocrine activation of the Wnt/beta-catenin pathway in macrophage cell lines.
Anagnostou SH, Shepherd PR
Biochem J 2008 Dec 1 416(2):211-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alex Toker
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 PPAR{gamma} and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale.
Lefterova MI, Zhang Y, …, Liu XS, Lazar MA
Genes Dev 2008 Nov 1 22(21):2941-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew D. Sharrocks
Evaluated 18 Nov 2008

Recommended
F1000 Factor 3.0

New Finding
 Persistent epigenetic differences associated with prenatal exposure to famine in humans.
Heijmans BT, Tobi EW, …, Slagboom PE, Lumey LH
Proc Natl Acad Sci U S A 2008 Nov 4 105(44):17046-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Wolf Reik
Evaluated 18 Nov 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs.
Hirota K, Miyoshi T, …, Shibata T, Ohta K
Nature 2008 Nov 6 456(7218):130-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Daniel Reines
Evaluated 18 Nov 2008


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