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Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
The establishment of gene silencing at single-cell resolution.
Osborne EA, Dudoit S, Rine J
Nat Genet 2009 Jul 41(7):800-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Fyodor Urnov
Evaluated 2 Jul 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
DnaAcos hyperinitiates by circumventing regulatory pathways that control the frequency of initiation in Escherichia coli.
Felczak MM, Kaguni JM
Mol Microbiol 2009 Jun 72(6):1348-63 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Marinus
Evaluated 1 Jul 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Female meiotic sex chromosome inactivation in chicken.
Schoenmakers S, Wassenaar E, …, Grootegoed JA, Baarends WM
PLoS Genet 2009 May 5(5):e1000466 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carmen Sapienza
Evaluated 1 Jul 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Specific genomic sequences of E. coli promote replicational initiation by directly reactivating ADP-DnaA.
Fujimitsu K, Senriuchi T, Katayama T
Genes Dev 2009 May 15 23(10):1221-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Marinus
Evaluated 30 Jun 2009

Must Read
F1000 Factor 6.0

New Finding
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance.
Tateishi K, Okada Y, Kallin EM, Zhang Y
Nature 2009 Apr 9 458(7239):757-61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Nicole de Wit and Michael Muller
Evaluated 30 Jun 2009

Recommended
F1000 Factor 3.0

New Finding
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting.
Donohoe ME, Silva SS, …, Xu N, Lee JT
Nature 2009 Jun 17 [abstract on PubMed] [related articles] [full text]
Selected by | Elisabetta Tabolacci and Giovanni Neri
Evaluated 26 Jun 2009

Recommended
F1000 Factor 3.0

Confirmation
New Finding
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice.
Lei K, Zhang X, …, Xu R, Han M
Proc Natl Acad Sci U S A 2009 Jun 9 [abstract on PubMed] [related articles] [full text]
Selected by | Alexandra Fridkin and Yosef Gruenbaum
Evaluated 25 Jun 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Epigenetic temporal control of mouse Hox genes in vivo.
Soshnikova N, Duboule D
Science 2009 Jun 5 324(5932):1320-3 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gregory Wray
Evaluated 23 Jun 2009

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Tech Advance
Lateral microtubule bundles promote chromosome alignment during acentrosomal oocyte meiosis.
Wignall SM, Villeneuve AM
Nat Cell Biol 2009 Jun 14 [abstract on PubMed] [related articles] [full text]
Selected by | Bob Goldstein
Evaluated 22 Jun 2009

Must Read
F1000 Factor 4.8

Confirmation
Hypothesis
New Finding
Tech Advance
A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei.
Boothroyd CE, Dreesen O, …, Cross GA, Papavasiliou FN
Nature 2009 May 14 459(7244):278-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Barbara Papadopoulou / Christine Clayton
First evaluation 22 Jun 2009 | Latest evaluation 24 Jun 2009


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