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Must Read
F1000 Factor
6.0
New Finding
Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation.
Carvajal G, Rodríguez-Vita J, …, Mezzano SA, Ruiz-Ortega M
Kidney Int
2008 Sep
74
(5):585-95 [
abstract on PubMed
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full text
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Selected by
| Norma A. Bobadilla
Evaluated 5 Sep 2008
Must Read
F1000 Factor
6.0
New Finding
TRPP2 and TRPV4 form a polymodal sensory channel complex.
Köttgen M, Buchholz B, …, Kuehn EW, Walz G
J Cell Biol
2008 Aug 11
182
(3):437-47 [
abstract on PubMed
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Selected by
| Jens Leipziger with Helle A. Praetorius
Evaluated 4 Sep 2008
Must Read
F1000 Factor
6.0
New Finding
Novel Drug Target
Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro.
Wang H, Yoshiko Y, …, Aubin JE, Maeda N
J Bone Miner Res
2008 Jun
23
(6):939-48 [
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Selected by
| Eleanor Lederer
Evaluated 3 Sep 2008
Must Read
F1000 Factor
6.0
New Finding
Refutation
Do mammals make all their own inositol hexakisphosphate?
Letcher AJ, Schell MJ, Irvine RF
Biochem J
2008 Aug 6 [
abstract on PubMed
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Selected by
| Steve Shears
Evaluated 2 Sep 2008
Recommended
F1000 Factor
3.0
New Finding
Novel Drug Target
Effects of intrathecal injection of a hyperpolarization-activated channel (I(h)) inhibitor ZD7288 on bladder function in urethane-anesthetized rats.
Masuda N, Masuda H, …, de Groat WC, Yoshimura N
Neurourol Urodyn
2008 Jul 18 [
abstract on PubMed
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full text
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Selected by
| Rodolfo Testa
Evaluated 1 Sep 2008
Recommended
F1000 Factor
3.0
New Finding
Klotho is a target gene of PPAR-gamma.
Zhang H, Li Y, …, Chien S, Wang N
Kidney Int
2008 Jun 11 [
abstract on PubMed
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Selected by
| Carolyn Ecelbarger
Evaluated 27 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
Tech Advance
Integrated pathway analysis of rat urine metabolic profiles and kidney transcriptomic profiles to elucidate the systems toxicology of model nephrotoxicants.
Xu EY, Perlina A, …, Aslamkhan AG, Xu Q
Chem Res Toxicol
2008 Aug
21
(8):1548-61 [
abstract on PubMed
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Selected by
| Bruce Car
Evaluated 27 Aug 2008
Must Read
F1000 Factor
6.0
Hypothesis
New Finding
Dominant and Redundant Functions of TFIID Involved in the Regulation of Hepatic Genes
Tatarakis A, Margaritis T, …, Tora L, Talianidis I
Molecular Cell
2008
31
:531-543 [
full text
]
Selected by
| Tony Weil
Evaluated 26 Aug 2008
Must Read
F1000 Factor
6.0
Hypothesis
New Finding
Murine TNF(DeltaARE) Crohn's disease model displays diminished expression of intestinal Ca2+ transporters.
Huybers S, Apostolaki M, …, Bindels RJ, Hoenderop JG
Inflamm Bowel Dis
2008 Jun
14
(6):803-11 [
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Selected by
| Indu Ambudkar
Evaluated 20 Aug 2008
Recommended
F1000 Factor
3.0
New Finding
Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney.
Toma I, Kang JJ, …, Meer E, Peti-Peterdi J
J Clin Invest
2008 Jul
118
(7):2526-34 [
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Selected by
| Matthew Breyer
Evaluated 20 Aug 2008
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