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Recommended
F1000 Factor 3.0

Hypothesis
The "metallo-specific" response of proteins: a perspective based on the Escherichia coli transcriptional regulator NikR.
Wang SC, Dias AV, Zamble DB
Dalton Trans 2009 Apr 14 (14):2459-66 [abstract on PubMed] [related articles] [full text]
Selected by | Crisjoe Joseph and Michael Maroney
Evaluated 3 Jul 2009

Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
The establishment of gene silencing at single-cell resolution.
Osborne EA, Dudoit S, Rine J
Nat Genet 2009 Jul 41(7):800-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Fyodor Urnov
Evaluated 2 Jul 2009

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Tailoring RNA modular units on a common scaffold: a modular ribozyme with a catalytic unit for beta-nicotinamide mononucleotide-activated RNA ligation.
Fujita Y, Furuta H, Ikawa Y
RNA 2009 May 15(5):877-88 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Aaron S. Burton and Niles Lehman
Evaluated 2 Jul 2009

Must Read
F1000 Factor 6.0

Confirmation
New Finding
Tech Advance
A dictionary for protein side-chain entropies from NMR order parameters.
Li DW, Brüschweiler R
J Am Chem Soc 2009 Jun 3 131(21):7226-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mikael Akke
Evaluated 2 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
DNA synthesis across an abasic lesion by human DNA polymerase iota.
Nair DT, Johnson RE, …, Prakash S, Aggarwal AK
Structure 2009 Apr 15 17(4):530-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sylvie Doublie
Evaluated 1 Jul 2009

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
TARP modulation of synaptic AMPA receptor trafficking and gating depends on multiple intracellular domains.
Milstein AD, Nicoll RA
Proc Natl Acad Sci U S A 2009 Jun 22 [abstract on PubMed] [related articles] [full text]
Selected by | Michael Ehlers
Evaluated 30 Jun 2009

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
Specific genomic sequences of E. coli promote replicational initiation by directly reactivating ADP-DnaA.
Fujimitsu K, Senriuchi T, Katayama T
Genes Dev 2009 May 15 23(10):1221-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Martin Marinus
Evaluated 30 Jun 2009

Recommended
F1000 Factor 3.0

New Finding
Lymphoid tissue-specific homing of bone marrow-derived dendritic cells.
Creusot RJ, Yaghoubi SS, …, Gambhir SS, Fathman CG
Blood 2009 Jun 25 113(26):6638-47 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Serreze
Evaluated 30 Jun 2009

Recommended
F1000 Factor 3.0

Confirmation
Structural insight into recruitment of translesion DNA polymerase Dpo4 to sliding clamp PCNA.
Xing G, Kirouac K, …, Bell SD, Ling H
Mol Microbiol 2009 Feb 71(3):678-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Titia Sixma
Evaluated 30 Jun 2009

Recommended
F1000 Factor 3.0

Tech Advance
A pyrrolysine analogue for protein click chemistry.
Fekner T, Li X, Lee MM, Chan MK
Angew Chem Int Ed Engl 2009 48(9):1633-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jan Grunewald
Evaluated 30 Jun 2009


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