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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Novel Drug Target
CRITICAL ROLE OF ACROLEIN IN SECONDARY INJURY FOLLOWING EX VIVO SPINAL CORD TRAUMA.
Hamann K, Durkes A, …, Pond A, Shi R
J Neurochem 2008 Aug 14 [abstract on PubMed] [related articles] [full text]
Selected by | Philip Burcham
Evaluated 5 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
A latitudinal cline in the Chinook salmon (Oncorhynchus tshawytscha) Clock gene: evidence for selection on PolyQ length variants.
O'Malley KG, Banks MA
Proc Biol Sci 2008 Aug 19 [abstract on PubMed] [related articles] [full text]
Selected by | Fred Allendorf
Evaluated 4 Sep 2008

Must Read
F1000 Factor 6.4

Confirmation
New Finding
Tech Advance
Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer.
Gubbels SP, Woessner DW, …, Ricci AJ, Brigande JV
Nature 2008 Aug 27 [abstract on PubMed] [related articles] [full text]
Selected by | Harukazu Nakamura / Andy Groves
Evaluated 4 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
Premotor sympathetic neurons of conditioned fear in the rat.
Carrive P, Gorissen M
Eur J Neurosci 2008 Aug 28(3):428-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Roger Dampney
Evaluated 4 Sep 2008

Recommended
F1000 Factor 3.0

Confirmation
Hypothesis
Genomic stability and tumour suppression by the APC/C cofactor Cdh1.
García-Higuera I, Manchado E, …, Moreno S, Malumbres M
Nat Cell Biol 2008 Jul 10(7):802-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Maria Blasco
Evaluated 3 Sep 2008

Exceptional
F1000 Factor 9.0

New Finding
Novel Drug Target
The incentive salience of alcohol: translating the effects of genetic variant in CNR1.
Hutchison KE, Haughey H, …, Horton WJ, Filbey F
Arch Gen Psychiatry 2008 Jul 65(7):841-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Markus Heilig
Evaluated 3 Sep 2008

Exceptional
F1000 Factor 9.0

New Finding
Individual premotor drive pulses, not time-varying synergies, are the units of adjustment for limb trajectories constructed in spinal cord.
Kargo WJ, Giszter SF
J Neurosci 2008 Mar 5 28(10):2409-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Neville Hogan
Evaluated 2 Sep 2008

Must Read
F1000 Factor 6.0

New Finding
Misfolded proteins partition between two distinct quality control compartments.
Kaganovich D, Kopito R, Frydman J
Nature 2008 Aug 28 454(7208):1088-95 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arlen Johnson
Evaluated 2 Sep 2008

Must Read
F1000 Factor 6.0

New Finding
Intramolecular activation mechanism of the dictyostelium LRRK2-homolog Roco protein GbpC.
van Egmond WN, Kortholt A, …, Keizer-Gunnink I, van Haastert PJ
J Biol Chem 2008 Aug 14 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jeffrey Williams
Evaluated 2 Sep 2008

Recommended
F1000 Factor 3.0

New Finding
Novel Drug Target
Effects of intrathecal injection of a hyperpolarization-activated channel (I(h)) inhibitor ZD7288 on bladder function in urethane-anesthetized rats.
Masuda N, Masuda H, …, de Groat WC, Yoshimura N
Neurourol Urodyn 2008 Jul 18 [abstract on PubMed] [related articles] [full text]
Selected by | Rodolfo Testa
Evaluated 1 Sep 2008


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