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Recommended
F1000 Factor 3.0

Refutation
 The chemokine receptor Cxcr3 is not essential for acute cardiac allograft rejection in mice and rats.
Zerwes HG, Li J, …, Thoma G, Luckow B
Am J Transplant 2008 Aug 8(8):1604-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mohamed Sayegh with Jessamyn Bagley
Evaluated 29 Aug 2008

Must Read
F1000 Factor 6.0

New Finding
Controversial
 TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation.
Ahn S, Lee G, …, Restifo NP, Kim MG
PLoS Biol 2008 Aug 5 6(8):e191 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Gerald Spangrude
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Unprecedented immunosuppressive polyketides from Daldinia eschscholzii, a mantis-associated fungus.
Zhang YL, Ge HM, …, Song YC, Tan RX
Angew Chem Int Ed Engl 2008 47(31):5823-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dennis Hall
Evaluated 29 Aug 2008

Must Read
F1000 Factor 6.0

New Finding
 Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding.
Greer ER, Pérez CL, …, Lee BH, Ashrafi K
Cell Metab 2008 Aug 8(2):118-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Timothy Gilbertson
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Human Metastasis Regulator Protein H-Prune is a Short-Chain Exopolyphosphatase.
Tammenkoski M, Koivula K, …, Baykov AA, Lahti R
Biochemistry 2008 Aug 14 0 [abstract on PubMed] [related articles] [full text]
Selected by | Roberto Docampo
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

Tech Advance
 Antimicrobial Surfaces through Natural Product Hybrids.
Wach JY, Bonazzi S, Gademann K
Angew Chem Int Ed Engl 2008 Jul 31 47(37):7123-7126 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Günter Mayer
Evaluated 29 Aug 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
Controversial
 Fibroblast growth factor 2 restrains Ras-driven proliferation of malignant cells by triggering RhoA-mediated senescence.
Costa ET, Forti FL, …, Koga MM, Armelin HA
Cancer Res 2008 Aug 1 68(15):6215-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrius Kazlauskas
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

Tech Advance
 Deployable laboratory response to emergence of melioidosis in central Sri Lanka.
Inglis TJ, Merritt A, …, Thevanesam V, McInnes R
J Clin Microbiol 2008 Aug 20 [abstract on PubMed] [related articles] [full text]
Selected by | Gary Lum
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
 Smoothelin-B deficiency results in reduced arterial contractility, hypertension, and cardiac hypertrophy in mice.
Rensen SS, Niessen PM, …, De Mey JG, van Eys GJ
Circulation 2008 Aug 19 118(8):828-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Giulio Gabbiani
Evaluated 29 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Censoring of autoreactive B cell development by the pre-B cell receptor.
Keenan RA, De Riva A, …, Winkler TH, Mårtensson IL
Science 2008 Aug 1 321(5889):696-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dorothy Yuan
Evaluated 29 Aug 2008


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