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Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 The transcriptional program underlying the physiology of clostridial sporulation.
Jones SW, Paredes CJ, …, Senger RS, Papoutsakis ET
Genome Biol 2008 Jul 16 9(7):R114 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Juergen Wiegel
Evaluated 28 Aug 2008

Must Read
F1000 Factor 6.0

New Finding
 Nucleotide excision repair driven by the dissociation of CAK from TFIIH.
Coin F, Oksenych V, …, Blattner C, Egly JM
Mol Cell 2008 Jul 11 31(1):9-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Pengbo Zhou
Evaluated 28 Aug 2008

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Controversial
 The H19 locus acts in vivo as a tumor suppressor.
Yoshimizu T, Miroglio A, …, Jammes H, Dandolo L
Proc Natl Acad Sci U S A 2008 Aug 21 [abstract on PubMed] [related articles] [full text]
Selected by | Wolf Reik
Evaluated 28 Aug 2008

Recommended
F1000 Factor 3.0

Hypothesis
New Finding
 Retinoblastoma and Its Binding Partner MSI1 Control Imprinting in Arabidopsis.
Jullien PE, Mosquna A, …, Ohad N, Berger F
PLoS Biol 2008 Aug 12 6(8):e194 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Wolf Reik
Evaluated 28 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances.
Wang SS, Kamphuis W, …, Zhou JN, Swaab DF
Mol Psychiatry 2008 Aug 13(8):786-99, 741 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan Seckl
Evaluated 28 Aug 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Regulation of a eukaryotic gene by GTP-dependent start site selection and transcription attenuation.
Kuehner JN, Brow DA
Mol Cell 2008 Jul 25 31(2):201-11 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dinah Singer
Evaluated 27 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Species-specific positive selection of the male-specific lethal complex that participates in dosage compensation in Drosophila.
Rodriguez MA, Vermaak D, Bayes JJ, Malik HS
Proc Natl Acad Sci U S A 2007 Sep 25 104(39):15412-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Fry
Evaluated 27 Aug 2008

Recommended
F1000 Factor 3.0

Tech Advance
 Transcription monitoring using fused RNA with a dye-binding light-up aptamer as a tag: a blue fluorescent RNA.
Sando S, Narita A, Hayami M, Aoyama Y
Chem Commun 2008 3858-3860 [full text]
Selected by | Scott K. Silverman
Evaluated 27 Aug 2008

Must Read
F1000 Factor 6.0

Hypothesis
New Finding
 Dominant and Redundant Functions of TFIID Involved in the Regulation of Hepatic Genes
Tatarakis A, Margaritis T, …, Tora L, Talianidis I
Molecular Cell 2008 31:531-543 [full text]
Selected by | Tony Weil
Evaluated 26 Aug 2008

Recommended
F1000 Factor 3.0

New Finding
 Two highly related regulatory subunits of PP2A exert opposite effects on TGF-{beta}/Activin/Nodal signalling.
Batut J, Schmierer B, …, Hill CS, Howell M
Development 2008 Sep 135(17):2927-37 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kate Loveland
Evaluated 26 Aug 2008


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