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Recommended
F1000 Factor 3.0

New Finding
JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.
Santaguida M, Schepers K, …, Braun BS, Passegué E
Cancer Cell 2009 Apr 7 15(4):341-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | R. Katherine Hyde and Paul Liu
Evaluated 3 Jul 2009

Recommended
F1000 Factor 3.0

Hypothesis
Regulation, necessity, and the misinterpretation of knockouts.
Davies J
Bioessays 2009 Jun 24 [abstract on PubMed] [related articles] [full text]
Selected by | Sheila McCormick
Evaluated 3 Jul 2009

Must Read
F1000 Factor 6.0

New Finding
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.
Brydges SD, Mueller JL, …, Kastner DL, Hoffman HM
Immunity 2009 Jun 19 30(6):875-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jenny Ting
Evaluated 3 Jul 2009

Must Read
F1000 Factor 6.0

New Finding
A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses.
Meng G, Zhang F, …, Kitani A, Strober W
Immunity 2009 Jun 19 30(6):860-74 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jenny Ting
Evaluated 3 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
Identification of the pollen self-incompatibility determinant in Papaver rhoeas.
Wheeler MJ, de Graaf BH, …, Franklin FC, Franklin-Tong VE
Nature 2009 Jun 18 459(7249):992-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Smyth
Evaluated 3 Jul 2009

Must Read
F1000 Factor 6.0

New Finding
Biochemical Evidence for Translational Repression by Arabidopsis MicroRNAs.
Lanet E, Delannoy E, …, Voinnet O, Robaglia C
Plant Cell 2009 Jun 16 [abstract on PubMed] [related articles] [full text]
Selected by | Julia Kehr
Evaluated 3 Jul 2009

Recommended
F1000 Factor 3.0

Hypothesis
The role of behaviour in evolution: a search for mechanism.
Duckworth RA
Evol Ecol 2009 23:513-531 [full text]
Selected by | Isabel M. Smallegange and Tim Coulson
Evaluated 3 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
Novel Drug Target
The melanin-concentrating hormone system modulates cocaine reward.
Chung S, Hopf FW, …, Bonci A, Civelli O
Proc Natl Acad Sci U S A 2009 Apr 21 106(16):6772-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Audrey Seasholtz
Evaluated 3 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
Hematopoietic stem cell development is dependent on blood flow.
North TE, Goessling W, …, Dzierzak E, Zon LI
Cell 2009 May 15 137(4):736-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | R. Katherine Hyde and Paul Liu
Evaluated 2 Jul 2009

Exceptional
F1000 Factor 9.0

New Finding
Tech Advance
The establishment of gene silencing at single-cell resolution.
Osborne EA, Dudoit S, Rine J
Nat Genet 2009 Jul 41(7):800-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Fyodor Urnov
Evaluated 2 Jul 2009


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