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F1000 Factor 3.0

New Finding
 JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.
Santaguida M, Schepers K, …, Braun BS, Passegué E
Cancer Cell 2009 Apr 7 15(4):341-52 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | R. Katherine Hyde and Paul Liu
Evaluated 3 Jul 2009

Recommended
F1000 Factor 3.0

Hypothesis
 Regulation, necessity, and the misinterpretation of knockouts.
Davies J
Bioessays 2009 Jun 24 [abstract on PubMed] [related articles] [full text]
Selected by | Sheila McCormick
Evaluated 3 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
 Identification of the pollen self-incompatibility determinant in Papaver rhoeas.
Wheeler MJ, de Graaf BH, …, Franklin FC, Franklin-Tong VE
Nature 2009 Jun 18 459(7249):992-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Smyth
Evaluated 3 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
 Hematopoietic stem cell development is dependent on blood flow.
North TE, Goessling W, …, Dzierzak E, Zon LI
Cell 2009 May 15 137(4):736-48 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | R. Katherine Hyde and Paul Liu
Evaluated 2 Jul 2009

Must Read
F1000 Factor 6.0

New Finding
 Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut.
Jiang H, Patel PH, …, McEwen DG, Edgar BA
Cell 2009 Jun 26 137(7):1343-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yukiko Yamashita
Evaluated 2 Jul 2009

Recommended
F1000 Factor 3.0

Confirmation
New Finding
Tech Advance
 Novel persistence genes in Pseudomonas aeruginosa identified by high-throughput screening.
De Groote VN, Verstraeten N, …, Cornelis P, Michiels J
FEMS Microbiol Lett 2009 May 21 [abstract on PubMed] [related articles] [full text]
Selected by | Lawrence R. Mulcahy and Kim Lewis
Evaluated 2 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
 The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity.
Scott GN, DuHadaway J, …, Muller AJ, Mandik-Nayak L
J Immunol 2009 Jun 15 182(12):7509-17 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Howard Young
Evaluated 1 Jul 2009

Must Read
F1000 Factor 6.0

Confirmation
New Finding
Novel Drug Target
 Inhibition of the SDF-1/CXCR4 axis attenuates neonatal hypoxia-induced pulmonary hypertension.
Young KC, Torres E, …, Suguihara C, Hare JM
Circ Res 2009 Jun 5 104(11):1293-301 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kurt Stenmark
Evaluated 1 Jul 2009

Recommended
F1000 Factor 3.0

Hypothesis
 Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche.
Díaz-Flores L, Gutiérrez R, …, Martín-Vasallo P, Díaz-Flores L
Histol Histopathol 2009 Jul 24(7):909-69 [abstract on PubMed] [related articles] [order article]
Selected by | Kenneth Gross
Evaluated 1 Jul 2009

Recommended
F1000 Factor 3.0

New Finding
 Yurt, Coracle, Neurexin IV and the Na(+),K(+)-ATPase form a novel group of epithelial polarity proteins.
Laprise P, Lau KM, …, McGlade CJ, Tepass U
Nature 2009 Jun 25 459(7250):1141-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | David Bilder
Evaluated 30 Jun 2009


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