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 Sections for IMMUNOLOGY

SECTION
SCOPE
Allergy & hypersensitivityChemokines, complement & receptors
Cytokines & cytokine receptors in allergy
Eosinophils
Fc receptors & signalling mechanisms
Inhibitory receptors & mechanisms of inhibition
Mast cells
Specific diseases & therapy
T helper cells (TH1, TH2)
The genetic basis of hypersensitivity & environmental contribution

Antigen processing & recognitionAntigen processing & presentation
APCs & APC/T cell interaction
MHC, TCR, BcR structures

AutoimmunityBreakdown in tolerance
Environmental contribution
Etiology & pathogenesis
Genetics of autoimmunity
Organ specific autoimmunity
Systemic autoimmunity
Therapy

Cellular microbiology & pathogenesisAdhesion
Cellular signalling
Cellular trafficking & microbes
Disease models
Emerging microbial diseases
Host exploitation
Host invasion
Host-microbe interactions
Mechanisms of resistance & susceptibility
Persistence
Symbiosis
Toxins
Virulence factors: processing, delivery & gene regulation

Genetics of the immune systemAutoimmune gene mapping
Cytokines/interferon
Disease mapping
Gene super-families
Genomic sequence
Ig genetics
Immunoarrays
Immuno-evolution
MHC
Mouse immunogenetics/knock-outs
Primate genetics
Receptors
Regulation

Immune responseCooperation in effector responses
Coordination of innate & adaptive immune systems
Immune complexes & Fc receptors & c' receptors
Immunoendocrine networks
Lymphocyte trafficking
Lymphoid organ development & organization
Maturation of the immune response
Micro-environments (lymphocyte niches)
Regionalization

Immunity to infectionsAcquired responses
Antigen processing/presentation
Genetic susceptibility factors in hosts
Immune evasion by microbes
Inflammation & cytokines
Innate recognition of microbes
Pathogenesis & resistance
Specific, major infectious diseases

ImmunomodulationAntigen barriers to transplantation
Immunomodulation (including immunotherapy)
Immunosuppression
Mechanisms of graft rejection & GVHD
Tumour evasion of immune system
Tumour vaccines
Vaccination (including therapeutic & contraceptive vaccines)
Xenotransplantation

Immunopharmacology & hematologic pharmacologyAnemias
Anti-allergy drugs
Anti-inflammatory drugs
Cytokines as drug targets
Disorders of leukocytes (other than cancer)
Immunomodulating agents
Immunotherapy & vaccines
Immunotoxicology
Platelet disorders

Innate immunityBasophils
Complement
Eosinophils
Inflammation & mediators
Innate immunity
Innate immunity in lower organisms
Intracellular killing
Killer cells & killing mechanisms
Neutrophils
NK cells phagocytosis/scavenging
Opsonization

Leukocyte activationAntibody synthesis & class-switching (including hypermutation)
Germinal centers
T helper cells & their activation
T-cell, B-cell & NK activation & functions

Leukocyte developmentB cell differentiation
B cell regionalization
B cell specialization & memory
B cell tolerance
Cell migration
Hematopoietic stem cells
Lineage commitment
Peripheral tolerance & memory
Regionalization
T cell differentiation
T cell education in the thymus
V(D)J recombination

Leukocyte signalling & gene expressionB cells: antigen recognition
B cells: gene expression
B cells: other receptor systems
CD4/CD8
Mast cells, dendritic cells & macrophages: gene expression
Mast cells, dendritic cells & macrophages: receptors
NK cells: receptors
Platelets, neutrophils & other myeloid cells: receptors
T cells: co-stimulatory receptors
T cells: cytokine receptors
T cells: gene expression
T cells: receptors involved in antigen recognition
T cells: TNF & death receptors



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