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Hugues Abriel
Department of Pharmacology and Cardiology, Université de Lausanne, Lausanne, Switzerland

Faculty Member: PHYSIOLOGY > Cardiovascular physiology/circulation [ since 1 June 2005 ]
[ Evaluations ]
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Evaluations

Sudden cardiac arrest associated with early repolarization.
Haïssaguerre M, Derval N, …, Klein GJ, Clémenty J
N Engl J Med 2008 May 8 358(19):2016-23 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel
Evaluated 3 Jun 2008


Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation.
Darbar D, Kannankeril PJ, …, George AL, Roden DM
Circulation 2008 Apr 15 117(15):1927-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel
Evaluated 25 Apr 2008

Mutation of an A-kinase-anchoring protein causes long-QT syndrome.
Chen L, Marquardt ML, …, Ackerman MJ, Kass RS
Proc Natl Acad Sci U S A 2007 Dec 26 104(52):20990-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 13 Mar 2008

Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway.
Lowe JS, Palygin O, …, Anderson ME, Mohler PJ
J Cell Biol 2008 Jan 14 180(1):173-86 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel
Evaluated 28 Jan 2008

Anti-KCNH2 antibody-induced long QT syndrome: novel acquired form of long QT syndrome.
Nakamura K, Katayama Y, …, Kurachi Y, Ohe T
J Am Coll Cardiol 2007 Oct 30 50(18):1808-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel
Evaluated 7 Dec 2007

PDZ domain binding selectivity is optimized across the mouse proteome.
Stiffler MA, Chen JR, …, Zaslavskaia LA, MacBeath G
Science 2007 Jul 20 317(5836):364-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas Biederer / Frances Arnold / John Ladbury / Hugues Abriel
Evaluated 13 Aug 2007

Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification.
Carrithers MD, Dib-Hajj S, …, Jonas EA, Waxman SG
J Immunol 2007 Jun 15 178(12):7822-32 [abstract on PubMed] [related articles] [order article]
Selected by | Hugues Abriel
Evaluated 13 Jun 2007

A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
Jarvis MF, Honore P, …, Faltynek CR, Krafte DS
Proc Natl Acad Sci U S A 2007 May 15 104(20):8520-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel / Sharona Gordon
Evaluated 4 May 2007


Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations.
Goldberg YP, MacFarlane J, …, Sherrington R, Hayden MR
Clin Genet 2007 Apr 71(4):311-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel
Evaluated 4 May 2007

Gating pore current in an inherited ion channelopathy.
Sokolov S, Scheuer T, Catterall WA
Nature 2007 Mar 1 446(7131):76-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Annette Dolphin / Gerald Zamponi / Louis Ptacek / Hugues Abriel
Evaluated 27 Mar 2007

Control of stress-dependent cardiac growth and gene expression by a microRNA.
van Rooij E, Sutherland LB, …, Hill J, Olson EN
Science 2007 Apr 27 316(5824):575-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel / Hans van Beek / Aniko Naray-Fejes-Toth
Evaluated 27 Mar 2007

Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor.
Ben-Chaim Y, Chanda B, …, Parnas I, Parnas H
Nature 2006 Nov 2 444(7115):106-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marcos Milla / Hugues Abriel
Evaluated 22 Dec 2006

Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD.
Remme CA, Verkerk AO, …, Veldkamp MW, Bezzina CR
Circulation 2006 Dec 12 114(24):2584-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel
Evaluated 19 Dec 2006

Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome.
Vatta M, Ackerman MJ, …, Kamp TJ, Towbin JA
Circulation 2006 Nov 14 114(20):2104-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 31 Oct 2006

Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation.
Olson TM, Alekseev AE, …, Jahangir A, Terzic A
Hum Mol Genet 2006 Jul 15 15(14):2185-91 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 30 Aug 2006

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation.
Gollob MH, Jones DL, …, Ebihara L, Bai D
N Engl J Med 2006 Jun 22 354(25):2677-88 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel / Eric Beyer
Evaluated 18 Aug 2006

Gastrointestinal symptoms in families of patients with an SCN5A-encoded cardiac channelopathy: evidence of an intestinal channelopathy.
Locke GR, Ackerman MJ, …, Thapa P, Farrugia G
Am J Gastroenterol 2006 Jun 101(6):1299-304 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel
Evaluated 7 Jul 2006

Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation.
Balijepalli RC, Foell JD, …, Hell JW, Kamp TJ
Proc Natl Acad Sci U S A 2006 May 9 103(19):7500-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel / Brett Adams
Evaluated 22 May 2006

A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y.
Plant LD, Bowers PN, …, Kittles RA, Goldstein SA
J Clin Invest 2006 Feb 116(2):430-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 10 Feb 2006

Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures.
Mantegazza M, Gambardella A, …, Wanke E, Quattrone A
Proc Natl Acad Sci U S A 2005 Dec 13 102(50):18177-82 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel / Anna-Elina Lehesjoki
Evaluated 15 Dec 2005

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias.
Lehnart SE, Wehrens XH, …, Conti M, Marks AR
Cell 2005 Oct 7 123(1):25-35 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Hugues Abriel
Evaluated 16 Nov 2005

Nontranscriptional regulation of cardiac repolarization currents by testosterone.
Bai CX, Kurokawa J, …, Nakaya H, Furukawa T
Circulation 2005 Sep 20 112(12):1701-10 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 10 Oct 2005

Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis.
Fraser SP, Diss JK, …, Coombes RC, Djamgoz MB
Clin Cancer Res 2005 Aug 1 11(15):5381-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 31 Aug 2005

Human cardiac potassium channel DNA polymorphism modulates access to drug-binding site and causes drug resistance.
Drolet B, Simard C, Mizoue L, Roden DM
J Clin Invest 2005 Aug 115(8):2209-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 31 Aug 2005

Phospholemman-phosphorylation mediates the beta-adrenergic effects on Na/K pump function in cardiac myocytes.
Despa S, Bossuyt J, …, Tucker AL, Bers DM
Circ Res 2005 Aug 5 97(3):252-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 14 Jul 2005

Mammalian electrophysiology on a microfluidic platform.
Ionescu-Zanetti C, Shaw RM, …, Jan LY, Lee LP
Proc Natl Acad Sci U S A 2005 Jun 28 102(26):9112-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 4 Jul 2005

Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations.
Splawski I, Timothy KW, …, Sanguinetti MC, Keating MT
Proc Natl Acad Sci U S A 2005 Jun 7 102(23):8089-96; discussion 8086-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Hugues Abriel
Evaluated 22 Jun 2005

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