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Mark Donowitz
Departments of Medicine/GI/Physiology, Johns Hopkins Medical Institute, Baltimore, United States of America

Head of Section: Pharmacology & Drug Discovery > Gastrointestinal Pharmacology [ since 18 January 2005 ]
[ Evaluations ]
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Evaluations

Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications.
Landau M, Herz K, Padan E, Ben-Tal N
J Biol Chem 2007 Dec 28 282(52):37854-63 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Donowitz
Evaluated 15 Nov 2007

Mechanism of Na+/H+ antiporting.
Arkin IT, Xu H, …, Shan Y, Shaw DE
Science 2007 Aug 10 317(5839):799-803 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Mark Donowitz / Ramon Serrano
Evaluated 31 Aug 2007

A sperm-specific Na+/H+ exchanger (sNHE) is critical for expression and in vivo bicarbonate regulation of the soluble adenylyl cyclase (sAC).
Wang D, Hu J, …, Moe OW, Garbers DL
Proc Natl Acad Sci U S A 2007 May 29 104(22):9325-30 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Donowitz
Evaluated 12 Jul 2007

Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation.
Ammar YB, Takeda S, …, Mori H, Wakabayashi S
EMBO J 2006 Jun 7 25(11):2315-25 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Donowitz
Evaluated 14 Jun 2006

Shank2 associates with and regulates Na+/H+ exchanger 3.
Han W, Kim KH, …, Kim E, Lee MG
J Biol Chem 2006 Jan 20 281(3):1461-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Donowitz
Evaluated 9 Jan 2006

Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo.
Clayburgh DR, Barrett TA, …, Mrsny RJ, Turner JR
J Clin Invest 2005 Oct 115(10):2702-15 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Donowitz
Evaluated 20 Dec 2005

Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane.
Utech M, Ivanov AI, …, Parkos CA, Nusrat A
Mol Biol Cell 2005 Oct 16(10):5040-52 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Donowitz
Evaluated 13 Sep 2005

Role of PDZK1 in membrane expression of renal brush border ion exchangers.
Thomson RB, Wang T, …, Kocher O, Aronson PS
Proc Natl Acad Sci U S A 2005 Sep 13 102(37):13331-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Donowitz
Evaluated 13 Sep 2005

Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger.
Gawenis LR, Greeb JM, …, Miller ML, Shull GE
J Biol Chem 2005 Apr 1 280(13):12781-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Donowitz
Evaluated 7 Feb 2005

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