 | Annette Dolphin
Department of Pharmacology, University College London, London, United Kingdom | | | Faculty Member: Cell Biology > Cell Signalling [ since 5 July 2001 ] |
| | [ Sponsorship ] [ Biography ] [ Evaluations ] | Sponsorship
Annette Dolphin sponsors free access to F1000 for Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Supporting F1000's initiative to make itself available to scientists in all countries, including free access to developing countries (more details). | Biography
Annette C. Dolphin received her BA in Natural Sciences (Biochemistry) from the University of Oxford and her PhD at the Institute of Psychiatry in London. She held postdoctoral fellowships at the College de France in Paris, and at Yale University, before returning to a post at the National Institute for Medical Research. She then took up a lectureship at St. George's Hospital Medical School, London, and was appointed to the chair of Pharmacology at the Royal Free Hospital School of Medicine, London, in 1990. Following the merger with University College London in 1997, she moved to the UCL campus. Her group is interested in the properties of voltage-dependent calcium channels, their modulation and expression in the nervous system. Utilising molecular biological, biochemical, immunocytochemical and electrophysiological techniques they examine how voltage-dependent calcium channels are assembled in the membrane, and are interested in assigning specific properties to particular regions of the hetero-oligomeric channel complex. Of particular interest is the mechanism of modulation of certain neuronal calcium channels by G protein activation, as this is a likely mechanism for the ubiquitous and highly important process of presynaptic inhibition of transmitter release. |
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