homefeedbacksupportlog on 30-Aug-2008 
  About F1000

 What is F1000 Biology?
 Key features
 How it's organized
 FAQs
 Faculties and sections
 Scope of sections
 List of Faculty Members
 The evaluation system
 Citing F1000
 Take a tour of the site
 Accessing fulltexts
 PubMed linkout
 How to subscribe
 Academic subscriptions
 Corporate subscriptions
 Try F1000 for free
 Who we are
 Media information
 Librarian resources
 Press releases
 In the press
 Developing countries
 F1000 Medicine
 Terms and conditions
 Privacy policy
 Contact us


Lee Gehrke
Department of Microbiology and Molecular Genetics, Massachusetts Institute of Technology, United States of America

Faculty Member: Cell Biology > Control of Gene Expression [ since 6 September 2002 ]
[ Evaluations ]
to email [Help]
Evaluations

Step-wise formation of eukaryotic double-row polyribosomes and circular translation of polysomal mRNA.
Kopeina GS, Afonina ZA, …, Vasiliev VD, Spirin AS
Nucleic Acids Res 2008 May 36(8):2476-88 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 10 Jul 2008

Double-stranded RNA-binding protein regulates vascular endothelial growth factor mRNA stability, translation, and breast cancer angiogenesis.
Vumbaca F, Phoenix KN, …, Han DK, Claffey KP
Mol Cell Biol 2008 Jan 28(2):772-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lee Gehrke
Evaluated 20 Mar 2008

Identification of novel small-molecule inhibitors of West Nile virus infection.
Noueiry AO, Olivo PD, …, Samuel M, Diamond MS
J Virol 2007 Nov 81(21):11992-2004 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lee Gehrke
Evaluated 7 Jan 2008

Nuclear factors are involved in hepatitis C virus RNA replication.
Isken O, Baroth M, …, Ostareck-Lederer A, Behrens SE
RNA 2007 Oct 13(10):1675-92 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lee Gehrke
Evaluated 25 Oct 2007

Viral translation is coupled to transcription in Sindbis virus-infected cells.
Sanz MA, Castelló A, Carrasco L
J Virol 2007 Jul 81(13):7061-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 26 Jun 2007

Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response.
Plumet S, Herschke F, …, Longhi S, Gerlier D
PLoS ONE 2007 2:e279 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 26 Mar 2007

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.
Saito T, Hirai R, …, Fujita T, Gale M
Proc Natl Acad Sci U S A 2007 Jan 9 104(2):582-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 22 Jan 2007

Assembly of two independent populations of flock house virus particles with distinct RNA packaging characteristics in the same cell.
Venter PA, Schneemann A
J Virol 2007 Jan 81(2):613-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 12 Jan 2007

The double-stranded RNA binding protein 76:NF45 heterodimer inhibits translation initiation at the rhinovirus type 2 internal ribosome entry site.
Merrill MK, Gromeier M
J Virol 2006 Jul 80(14):6936-42 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 13 Jul 2006

Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2.
Yoshida M, Yoshida K, …, Wing SS, Sonenberg N
EMBO J 2006 May 3 25(9):1934-44 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 17 May 2006

Systematic identification of human mitochondrial disease genes through integrative genomics.
Calvo S, Jain M, …, Carr SA, Mootha VK
Nat Genet 2006 May 38(5):576-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lee Gehrke
Evaluated 24 Apr 2006

Structure of an archaeal virus capsid protein reveals a common ancestry to eukaryotic and bacterial viruses.
Khayat R, Tang L, …, Young M, Johnson JE
Proc Natl Acad Sci U S A 2005 Dec 27 102(52):18944-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Malcolm White / Lee Gehrke
Evaluated 14 Feb 2006

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation.
Bordeleau ME, Matthews J, …, Teesdale-Spittle P, Pelletier J
Proc Natl Acad Sci U S A 2005 Jul 26 102(30):10460-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 25 Aug 2005

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I.
Sumpter R, Loo YM, …, Lemon SM, Gale M
J Virol 2005 Mar 79(5):2689-99 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Robert Krug / Lee Gehrke
Evaluated 28 Jun 2005

Expression of a viral polymerase-bound host factor turns human cell lines permissive to a plant- and insect-infecting virus.
de Medeiros RB, Figueiredo J, Resende Rde O, De Avila AC
Proc Natl Acad Sci U S A 2005 Jan 25 102(4):1175-80 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 1 Feb 2005

Cytoplasmic dynein mediates adenovirus binding to microtubules.
Kelkar SA, Pfister KK, Crystal RG, Leopold PL
J Virol 2004 Sep 78(18):10122-32 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 18 Nov 2004

Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor.
Spahn CM, Jan E, …, Sarnow P, Frank J
Cell 2004 Aug 20 118(4):465-75 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lee Gehrke
Evaluated 9 Sep 2004

Alternate, virus-induced membrane rearrangements support positive-strand RNA virus genome replication.
Schwartz M, Chen J, …, Janda M, Ahlquist P
Proc Natl Acad Sci U S A 2004 Aug 3 101(31):11263-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 4 Aug 2004

TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus.
Le May N, Dubaele S, …, Bouloy M, Egly JM
Cell 2004 Feb 20 116(4):541-50 [abstract on PubMed] [related articles] [order article]
Selected by | Lee Gehrke
Evaluated 5 Apr 2004

Identification of many microRNAs that copurify with polyribosomes in mammalian neurons.
Kim J, Krichevsky A, …, Church GM, Ruvkun G
Proc Natl Acad Sci U S A 2004 Jan 6 101(1):360-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke / Claudia Bagni
Evaluated 27 Jan 2004

The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95.
Todd PK, Mack KJ, Malter JS
Proc Natl Acad Sci U S A 2003 Nov 25 100(24):14374-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 21 Nov 2003

Programming peptidomimetic syntheses by translating genetic codes designed de novo.
Forster AC, Tan Z, …, Cornish VW, Blacklow SC
Proc Natl Acad Sci U S A 2003 May 27 100(11):6353-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 9 Sep 2003

Single molecule profiling of alternative pre-mRNA splicing.
Zhu J, Shendure J, Mitra RD, Church GM
Science 2003 Aug 8 301(5634):836-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke / Gabriele Varani
Evaluated 9 Sep 2003

Yeast Lsm1p-7p/Pat1p deadenylation-dependent mRNA-decapping factors are required for brome mosaic virus genomic RNA translation.
Noueiry AO, Diez J, …, Chen J, Ahlquist P
Mol Cell Biol 2003 Jun 23(12):4094-106 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 11 Jun 2003

Role of the transmembrane domains of prM and E proteins in the formation of yellow fever virus envelope.
Op De Beeck A, Molenkamp R, …, Bredenbeek P, Dubuisson J
J Virol 2003 Jan 77(2):813-20 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 17 Apr 2003

A simple alfalfa seedling infection model for Pseudomonas aeruginosa strains associated with cystic fibrosis shows AlgT (sigma-22) and RhlR contribute to pathogenesis.
Silo-Suh L, Suh SJ, Sokol PA, Ohman DE
Proc Natl Acad Sci U S A 2002 Nov 26 99(24):15699-704 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 15 Nov 2002

Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replication.
Li W, Li Y, …, Moreno GT, Brinton MA
J Virol 2002 Dec 76(23):11989-2000 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lee Gehrke
Evaluated 11 Nov 2002

^Top  Back to Faculty Members


© 1999-2008 Biology Reports Ltd unless otherwise stated < info@f1000.com >   Terms and conditions   Legal info