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Dean Sheppard
Department of Medicine, University of California, San Francisco, San Francisco, United States of America

Faculty Member: IMMUNOLOGY > Allergy & hypersensitivity [ since 2 July 2001 ]
[ Evaluations ]
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Evaluations

Cyclin-dependent kinase inhibitors block leukocyte adhesion and migration.
Liu L, Schwartz B, …, Harlan JM, Schnapp LM
J Immunol 2008 Feb 1 180(3):1808-17 [abstract on PubMed] [related articles] [order article]
Selected by | Dean Sheppard
Evaluated 8 Feb 2008

A GABAergic system in airway epithelium is essential for mucus overproduction in asthma.
Xiang YY, Wang S, …, Yang X, Lu WY
Nat Med 2007 Jul 13(7):862-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dean Sheppard / Robert  Fecik
Evaluated 17 Jul 2007


CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells.
Schneider MA, Meingassner JG, …, Moore HD, Rot A
J Exp Med 2007 Apr 16 204(4):735-45 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard
Evaluated 19 Apr 2007

The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation.
Martin P, Diaz-Meco MT, Moscat J
EMBO J 2006 Aug 9 25(15):3524-33 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard
Evaluated 21 Aug 2006

IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis.
Fichtner-Feigl S, Strober W, …, Puri RK, Kitani A
Nat Med 2006 Jan 12(1):99-106 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dean Sheppard
Evaluated 16 Jan 2006


A critical control element for interleukin-4 memory expression in T helper lymphocytes.
Tykocinski LO, Hajkova P, …, Paul WE, Radbruch A
J Biol Chem 2005 Aug 5 280(31):28177-85 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Santa Jeremy Ono / Mark Bix / Dean Sheppard
Evaluated 10 Aug 2005

T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.
Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH
Science 2005 Jan 21 307(5708):430-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard / George Yap / Santa Jeremy Ono / Christopher A. Hunter / Thomas Graf
Evaluated 26 Jan 2005

JunD regulates lymphocyte proliferation and T helper cell cytokine expression.
Meixner A, Karreth F, Kenner L, Wagner EF
EMBO J 2004 Mar 24 23(6):1325-35 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard
Evaluated 18 May 2004

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity.
Akbari O, Stock P, …, DeKruyff RH, Umetsu DT
Nat Med 2003 May 9(5):582-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dean Sheppard / Santa Jeremy Ono
Evaluated 25 Apr 2003

A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells.
Solymar DC, Agarwal S, …, Alt FW, Rao A
Immunity 2002 Jul 17(1):41-50 [abstract on PubMed] [related articles] [order article]
Selected by | Dean Sheppard
Evaluated 2 Sep 2002

V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function.
Risma KA, Wang N, …, Chakraborty R, Hershey GK
J Immunol 2002 Aug 1 169(3):1604-10 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard
Evaluated 29 Aug 2002

Induction of T helper type 2 immunity by a point mutation in the LAT adaptor.
Aguado E, Richelme S, …, Malissen B, Malissen M
Science 2002 Jun 14 296(5575):2036-40 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard / Hans Acha-Orbea
Evaluated 19 Jun 2002

The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness.
Humbles AA, Lu B, …, Gerard NP, Gerard C
Proc Natl Acad Sci U S A 2002 Feb 5 99(3):1479-84 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard / Gerald Gleich
Evaluated 13 Mar 2002

Intrinsic AHR in IL-5 transgenic mice is dependent on CD4(+) cells and CD49d-mediated signaling.
Borchers MT, Crosby J, …, Lee JJ, Lee NA
Am J Physiol Lung Cell Mol Physiol 2001 Sep 281(3):L653-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard
Evaluated 7 Jan 2002

Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization.
Mazzoni A, Young HA, …, Visintin A, Segal DM
J Clin Invest 2001 Dec 108(12):1865-73 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Dean Sheppard
Evaluated 4 Jan 2002

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