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Randy Brutkiewicz
Department of Microbiology and Immunology, Indiana University School of Medicine, United States of America

Faculty Member: IMMUNOLOGY > Antigen processing & recognition [ since 2 February 2004 ]
[ Evaluations ]
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Evaluations

Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice.
Stirnemann K, Romero JF, …, Macdonald HR, Donda A
J Clin Invest 2008 Mar 118(3):994-1005 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Randy Brutkiewicz
Evaluated 14 May 2008

Type II NKT cell-mediated anergy induction in type I NKT cells prevents inflammatory liver disease.
Halder RC, Aguilera C, Maricic I, Kumar V
J Clin Invest 2007 Aug 117(8):2302-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Mark Smyth / Randy Brutkiewicz
Evaluated 3 Oct 2007

CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma.
Akbari O, Faul JL, …, DeKruyff RH, Umetsu DT
N Engl J Med 2006 Mar 16 354(11):1117-29 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Eckhard Podack / Santa Jeremy Ono / Randy Brutkiewicz / Toshinori Nakayama
Evaluated 8 May 2006


Characterization of two avian MHC-like genes reveals an ancient origin of the CD1 family.
Miller MM, Wang C, …, Brenner MB, Dascher CC
Proc Natl Acad Sci U S A 2005 Jun 14 102(24):8674-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Branch Moody / Randy Brutkiewicz
Evaluated 28 Oct 2005

Two CD1 genes map to the chicken MHC, indicating that CD1 genes are ancient and likely to have been present in the primordial MHC.
Salomonsen J, Sørensen MR, …, Skjødt K, Kaufman J
Proc Natl Acad Sci U S A 2005 Jun 14 102(24):8668-73 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Stephan Beck / David Branch Moody / Randy Brutkiewicz
Evaluated 28 Oct 2005

Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides.
Yu KO, Im JS, …, Besra GS, Porcelli SA
Proc Natl Acad Sci U S A 2005 Mar 1 102(9):3383-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Randy Brutkiewicz
Evaluated 29 Mar 2005

Critical proinflammatory and anti-inflammatory functions of different subsets of CD1d-restricted natural killer T cells during Trypanosoma cruzi infection.
Duthie MS, Kahn M, …, Kapur RP, Kahn SJ
Infect Immun 2005 Jan 73(1):181-92 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Randy Brutkiewicz
Evaluated 25 Feb 2005

Lysosomal glycosphingolipid recognition by NKT cells.
Zhou D, Mattner J, …, Teyton L, Bendelac A
Science 2004 Dec 3 306(5702):1786-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Grant Morahan / Randy Brutkiewicz
Evaluated 21 Dec 2004

CD1d-restricted T cell activation by nonlipidic small molecules.
Van Rhijn I, Young DC, …, Cheng TY, Moody DB
Proc Natl Acad Sci U S A 2004 Sep 14 101(37):13578-83 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Randy Brutkiewicz
Evaluated 15 Oct 2004

Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide.
Jahng A, Maricic I, …, Halder RC, Kumar V
J Exp Med 2004 Apr 5 199(7):947-57 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Torben Lund / Randy Brutkiewicz
Evaluated 15 Oct 2004

CD1d function is regulated by microsomal triglyceride transfer protein.
Brozovic S, Nagaishi T, …, Exley M, Blumberg RS
Nat Med 2004 May 10(5):535-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Randy Brutkiewicz
Evaluated 16 Jul 2004

Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.
Terabe M, Matsui S, …, Paul WE, Berzofsky JA
J Exp Med 2003 Dec 1 198(11):1741-52 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Randy Brutkiewicz
Evaluated 16 Jul 2004

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