Professor in Physiology King's College London

Interests epithelial sugar, salt and water transport; sugar transport and its control; free radicals in relation to metabolism; models of biological transport.

Lack of evidence in vivo for a remote effect of Escherichia coli heat stable enterotoxin on jejunal fluid absorption. Lucas ML, Duncan NW, …, McIlvenny TJ, Nelson YB Neurogastroenterol Motil 2008 May 20(5):532-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 8 Aug 2008 The Crystal Structure of a Sodium Galactose Transporter Reveals Mechanistic Insights into Na+/Sugar Symport. Faham S, Watanabe A, …, Wright EM, Abramson J Science 2008 Jul 3 [abstract on PubMed] [related articles] [full text] Selected by | Nathan Nelson / Gary Rudnick / Richard J Naftalin Evaluated 28 Jul 2008 Surface expression of epithelial na channel protein in rat kidney. Frindt G, Ergonul Z, Palmer LG J Gen Physiol 2008 Jun 131(6):617-27 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 3 Jun 2008 Molecular proximity of cystic fibrosis transmembrane conductance regulator and epithelial sodium channel assessed by fluorescence resonance energy transfer. Berdiev BK, Cormet-Boyaka E, …, Lukacs GL, Benos DJ J Biol Chem 2007 Dec 14 282(50):36481-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 19 Dec 2007 Insulin internalizes GLUT2 in the enterocytes of healthy but not insulin-resistant mice. Tobin V, Le Gall M, …, Leturque A, Brot-Laroche E Diabetes 2007 Dec 17 [abstract on PubMed] [related articles] [full text] Selected by | Richard J Naftalin Evaluated 17 Dec 2007 T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1. Margolskee RF, Dyer J, …, Mosinger B, Shirazi-Beechey SP Proc Natl Acad Sci U S A 2007 Sep 18 104(38):15075-80 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 9 Oct 2007 Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2. Mace OJ, Affleck J, Patel N, Kellett GL J Physiol 2007 Jul 1 582(Pt 1):379-92 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 9 Oct 2007 Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies. Friedman J, Kraus S, …, Schiff Y, Seger R Biochem J 2007 Aug 1 405(3):559-68 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin / Alex Toker Evaluated 18 Jul 2007 Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling. Hawkins BJ, Madesh M, Kirkpatrick CJ, Fisher AB Mol Biol Cell 2007 Jun 18(6):2002-12 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 26 Jun 2007 Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Ohsawa I, Ishikawa M, …, Asoh S, Ohta S Nat Med 2007 Jun 13(6):688-94 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 14 Jun 2007 Lectin conjugates as potent, nonabsorbable CFTR inhibitors for reducing intestinal fluid secretion in cholera. Sonawane ND, Zhao D, …, Galietta LJ, Verkman AS Gastroenterology 2007 Apr 132(4):1234-44 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 20 Apr 2007 Vascular reactivity in arterioles from normal and alloxan-diabetic mice: studies on single perfused islets. Lai EY, Jansson L, Patzak A, Persson AE Diabetes 2007 Jan 56(1):107-12 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 18 Apr 2007 Human erythrocyte membranes contain a cytochrome b561 that may be involved in extracellular ascorbate recycling. Su D, May JM, Koury MJ, Asard H J Biol Chem 2006 Dec 29 281(52):39852-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 23 Feb 2007 Urearetics: a small molecule screen yields nanomolar potency inhibitors of urea transporter UT-B. Levin MH, de la Fuente R, Verkman AS FASEB J 2007 Feb 21(2):551-63 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 26 Jan 2007 Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model. Fan X, Reneker LW, …, Ortwerth BJ, Monnier VM Proc Natl Acad Sci U S A 2006 Nov 7 103(45):16912-7 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 14 Nov 2006 Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis. Myerburg MM, Butterworth MB, …, Kleyman TR, Pilewski JM J Biol Chem 2006 Sep 22 281(38):27942-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 25 Sep 2006 Ouabain affinity determining residues lie close to the Na/K pump ion pathway. Artigas P, Gadsby DC Proc Natl Acad Sci U S A 2006 Aug 15 103(33):12613-8 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 22 Aug 2006 Modulation and compensation of the mRNA expression of energy related transporters in the brain of glucose transporter 1-deficient mice. Ohtsuki S, Kikkawa T, Hori S, Terasaki T Biol Pharm Bull 2006 Aug 29(8):1587-91 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 15 Aug 2006 Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platform. Wang JK, Portbury S, …, Warner DS, Lo DC Proc Natl Acad Sci U S A 2006 Jul 5 103(27):10461-6 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 13 Jul 2006 Evidence against functionally significant aquaporin expression in mitochondria. Yang B, Zhao D, Verkman AS J Biol Chem 2006 Jun 16 281(24):16202-6 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 19 Jun 2006 Epithelial fluid transport: protruding macromolecules and space charges can bring about electro-osmotic coupling at the tight junctions. Rubashkin A, Iserovich P, Hernández JA, Fischbarg J J Membr Biol 2005 Dec 208(3):251-63 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 31 May 2006 Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice. Rojek A, Füchtbauer EM, …, Frøkiaer J, Nielsen S Proc Natl Acad Sci U S A 2006 Apr 11 103(15):6037-42 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin / John Mullins Evaluated 20 Apr 2006 Long-term metformin treatment stimulates cardiomyocyte glucose transport through an AMP-activated protein kinase-dependent reduction in GLUT4 endocytosis. Yang J, Holman GD Endocrinology 2006 Jun 147(6):2728-36 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 28 Mar 2006 Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells. Kruidenier L, MacDonald TT, …, Pender SL, Sanderson IR Gastroenterology 2006 Jan 130(1):127-36 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 21 Mar 2006 Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7). Manolescu A, Salas-Burgos AM, Fischbarg J, Cheeseman CI J Biol Chem 2005 Dec 30 280(52):42978-83 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 14 Mar 2006 Water transport by Na+-coupled cotransporters of glucose (SGLT1) and of iodide (NIS). The dependence of substrate size studied at high resolution. Zeuthen T, Belhage B, Zeuthen E J Physiol 2006 Feb 1 570(Pt 3):485-99 [abstract on PubMed] [related articles] [FREE full text] Selected by | Richard J Naftalin Evaluated 2 Mar 2006 Escherichia coli heat stable (STa) enterotoxin and the upper small intestine: lack of evidence in vivo for net fluid secretion. Lucas ML, Thom MM, …, McIlvenny TJ, Nelson YB J Membr Biol 2005 Jul 206(1):29-42 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Richard J Naftalin Evaluated 2 Mar 2006

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