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Tom Misteli
National Cancer Institute, National Cancer Institute, National Institutes of Health (NIH), Bethesda, United States of America

Faculty Member: Cell Biology > Nuclear Structure & Function [ since 26 January 2005 ]
[ Evaluations ]
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Evaluations

An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles.
Clemson CM, Hutchinson JN, …, Chess A, Lawrence JB
Mol Cell 2009 Feb 11 [abstract on PubMed] [related articles] [full text]
Selected by | Tom Misteli
Evaluated 26 Feb 2009

MEN{varepsilon}/{beta} noncoding RNAs are essential for structural integrity of nuclear paraspeckles.
Sasaki YT, Ideue T, …, Mituyama T, Hirose T
Proc Natl Acad Sci U S A 2009 Feb 2 [abstract on PubMed] [related articles] [full text]
Selected by | Tom Misteli
Evaluated 26 Feb 2009

Species-specific transcription in mice carrying human chromosome 21.
Wilson MD, Barbosa-Morais NL, …, Tavaré S, Odom DT
Science 2008 Oct 17 322(5900):434-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yoav Gilad / Kenneth Zaret / Deyou Zheng / Jose M. Jimenez-Gomez and Julin Maloof / Reza Kalhor and Lin Chen / Evi Soutoglou and Tom Misteli / Heng Zhu
Evaluated 24 Nov 2008

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.
Goodarzi AA, Noon AT, …, Löbrich M, Jeggo PA
Mol Cell 2008 Jul 25 31(2):167-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Anindya Dutta / Evi Soutoglou and Tom Misteli / Michael B. Yaffe
Evaluated 29 Aug 2008

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.
Chowdhury D, Xu X, …, Pfeifer GP, Lieberman J
Mol Cell 2008 Jul 11 31(1):33-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Evi Soutoglou and Tom Misteli
Evaluated 29 Jul 2008

Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies.
Zhang YQ, Sarge KD
J Cell Biol 2008 Jul 7 [abstract on PubMed] [related articles] [full text]
Selected by | Tom Misteli
Evaluated 16 Jul 2008

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions.
Mili S, Moissoglu K, Macara IG
Nature 2008 May 1 453(7191):115-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli / Dafna Bar-Sagi / Yukiko Yamashita / Vivian Tang / Irina Kaverina
Evaluated 7 May 2008

A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs.
Mellman DL, Gonzales ML, …, Kendziorski C, Anderson RA
Nature 2008 Feb 21 451(7181):1013-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli / Miles Wilkinson / Susan Wente / Gabriele Varani / Steve Shears
Evaluated 3 Mar 2008

The molecular architecture of the nuclear pore complex.
Alber F, Dokudovskaya S, …, Sali A, Rout MP
Nature 2007 Nov 29 450(7170):695-701 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Petra Fromme / Tom Misteli / Paul Clarke
Evaluated 18 Dec 2007

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.
Passos JF, Saretzki G, …, Kirkwood TB, von Zglinicki T
PLoS Biol 2007 May 5(5):e110 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tom Misteli
Evaluated 8 May 2007

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
Niedernhofer LJ, Garinis GA, …, Jaspers NG, Hoeijmakers JH
Nature 2006 Dec 21 444(7122):1038-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli
Evaluated 5 Jan 2007

A genomic code for nucleosome positioning.
Segal E, Fondufe-Mittendorf Y, …, Wang JP, Widom J
Nature 2006 Aug 17 442(7104):772-8 [abstract on PubMed] [related articles] [order article]
Selected by | Brad Bernstein / Tom Misteli / Kerry Bloom / Nick Rhind / James Bone / Francesc Posas / Michael Meisterernst / Leonie Ringrose / Gabriele Varani
Evaluated 25 Aug 2006

Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence.
Shopland LS, Lynch CR, …, Bult CJ, O'Brien TP
J Cell Biol 2006 Jul 3 174(1):27-38 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jane Hewitt / Tom Misteli
Evaluated 14 Aug 2006

The reversibility of mitotic exit in vertebrate cells.
Potapova TA, Daum JR, …, Stukenberg PT, Gorbsky GJ
Nature 2006 Apr 13 440(7086):954-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tom Misteli / Linda Wordeman / Claire Walczak / Kerry Bloom
Evaluated 21 Apr 2006

The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C.
Kishore S, Stamm S
Science 2006 Jan 13 311(5758):230-2 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Thomas Blumenthal / James Gusella / Tom Misteli / Andrea Barta / Laurence H. Tecott
Evaluated 2 Feb 2006

Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT.
Blaustein M, Pelisch F, …, Coso OA, Srebrow A
Nat Struct Mol Biol 2005 Dec 12(12):1037-44 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli
Evaluated 19 Dec 2005

Measurement of the contributions of 1D and 3D pathways to the translocation of a protein along DNA.
Gowers DM, Wilson GG, Halford SE
Proc Natl Acad Sci U S A 2005 Nov 1 102(44):15883-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tom Misteli / James Stivers
Evaluated 4 Nov 2005

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells.
Fujiwara T, Bandi M, …, Bronson RT, Pellman D
Nature 2005 Oct 13 437(7061):1043-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli / Stephen Doxsey / Domenico Grieco / Lucio Comai
Evaluated 19 Oct 2005

Genomic instability in laminopathy-based premature aging.
Liu B, Wang J, …, Tryggvason K, Zhou Z
Nat Med 2005 Jul 11(7):780-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yosef Gruenbaum / Tom Misteli
Evaluated 12 Jul 2005

Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes.
Bolzer A, Kreth G, …, Speicher MR, Cremer T
PLoS Biol 2005 May 3(5):e157 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tom Misteli
Evaluated 6 Jun 2005

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.
Gorgoulis VG, Vassiliou LV, …, Kittas C, Halazonetis TD
Nature 2005 Apr 14 434(7035):907-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli / Susan Forsburg / Thomas Ried
Evaluated 20 Apr 2005

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Bartkova J, Horejsí Z, …, Lukas J, Bartek J
Nature 2005 Apr 14 434(7035):864-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli / Michael B. Yaffe / Susan Forsburg
Evaluated 20 Apr 2005

Genomic characterization reveals a simple histone H4 acetylation code.
Dion MF, Altschuler SJ, Wu LF, Rando OJ
Proc Natl Acad Sci U S A 2005 Apr 12 102(15):5501-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jurg Bahler / Tom Misteli
Evaluated 20 Apr 2005

A systems analysis of importin-{alpha}-{beta} mediated nuclear protein import.
Riddick G, Macara IG
J Cell Biol 2005 Mar 28 168(7):1027-38 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Tom Misteli / Murray Stewart
Evaluated 13 Apr 2005

A role for PML3 in centrosome duplication and genome stability.
Xu ZX, Zou WX, Lin P, Chang KS
Mol Cell 2005 Mar 4 17(5):721-32 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli
Evaluated 9 Mar 2005

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