Faculty of 1000 Biology | Faculty member: Ian Hall

6-Jul-2008

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	Ian Hall Department of Therapeutics and Molecular Medicine, University Hospital of Nottingham, Nottingham, United Kingdom
	Head of Section: PHARMACOLOGY & DRUG DISCOVERY > Respiratory pharmacology [ since 15 June 2006 ]

[ Evaluations ]

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Evaluations

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Rasmussen SG, Choi HJ, …, Weis WI, Kobilka BK
Nature 2007 Nov 15 450(7168):383-7 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Leonardo Pardo / Fred Dyda / Carmen Dessauer / Arthur Christopoulos / Patricia C. Weber / Ian Hall / Marc Caron / Stephan Nussberger
Evaluated 13 Dec 2007

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
Binshtok AM, Bean BP, Woolf CJ
Nature 2007 Oct 4 449(7162):607-10 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Bernd Nilius / Ian Hall / Michael Andresen / David Triggle / Gavril Pasternak / Emery Brown / Jaime García-Añoveros
Evaluated 15 Oct 2007

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome.
Minegishi Y, Saito M, …, Metin A, Karasuyama H
Nature 2007 Aug 30 448(7157):1058-62 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Mary Dinauer / Ian Hall / Mercedes Rincon
Evaluated 11 Oct 2007

Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.
Ago H, Kanaoka Y, …, Austen KF, Miyano M
Nature 2007 Aug 2 448(7153):609-12 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Ian Hall
Evaluated 22 Aug 2007

Orai proteins interact with TRPC channels and confer responsiveness to store depletion.
Liao Y, Erxleben C, …, Armstrong DL, Birnbaumer L
Proc Natl Acad Sci U S A 2007 Mar 13 104(11):4682-7 [abstract on PubMed] [related articles] [FREE full text]

Selected by | Ian Hall
Evaluated 4 Apr 2007

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
Macpherson LJ, Dubin AE, …, Cravatt BF, Patapoutian A
Nature 2007 Feb 1 445(7127):541-5 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Ian Hall
Evaluated 20 Feb 2007

CRACM1 multimers form the ion-selective pore of the CRAC channel.
Vig M, Beck A, …, Kinet JP, Penner R
Curr Biol 2006 Oct 24 16(20):2073-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Ian Hall
Evaluated 16 Jan 2007

Genome-wide analysis of mammalian promoter architecture and evolution.
Carninci P, Sandelin A, …, Hume DA, Hayashizaki Y
Nat Genet 2006 Jun 38(6):626-35 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Andrew S. McCallion / Ulf Pettersson / Ian Hall
Evaluated 30 Nov 2006

Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai.
Yeromin AV, Zhang SL, …, Safrina O, Cahalan MD
Nature 2006 Sep 14 443(7108):226-9 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Roger Hardie / Angus Nairn / Anthony Means / Ian Hall
Evaluated 5 Oct 2006

Orai1 is an essential pore subunit of the CRAC channel.
Prakriya M, Feske S, …, Rao A, Hogan PG
Nature 2006 Sep 14 443(7108):230-3 [abstract on PubMed] [related articles] [full text] [order article]

Selected by | Roger Hardie / Angus Nairn / Ian Hall / Anthony Means
Evaluated 28 Sep 2006

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