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Matthew O'Connell
Ruttenberg Cancer Center, Mount Sinai School of Medicine, United States of America

Faculty Member: CELL BIOLOGY > Cell growth & division [ since 7 November 2003 ]
[ Evaluations ]
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Evaluations

Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.
Sidi S, Sanda T, …, D'Andrea AA, Look AT
Cell 2008 May 30 133(5):864-77 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Abrams / Sharad Kumar / Matthew O'Connell / Surender Kharbanda
Evaluated 11 Jun 2008

UV irradiation induces a postreplication DNA damage checkpoint.
Callegari AJ, Kelly TJ
Proc Natl Acad Sci U S A 2006 Oct 24 103(43):15877-82 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Teresa Wang / Antony Carr / Nick Rhind / Matthew O'Connell
Evaluated 28 Feb 2007

TopBP1 activates the ATR-ATRIP complex.
Kumagai A, Lee J, Yoo HY, Dunphy WG
Cell 2006 Mar 10 124(5):943-55 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Rouse / Antony Carr / Tim Humphrey / Matthew O'Connell / Stephen Elledge / Stephen Jackson
Evaluated 21 Apr 2006

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.
Bhoumik A, Takahashi S, …, Jones N, Ronai Z
Mol Cell 2005 May 27 18(5):577-87 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Robert Abraham / Matthew O'Connell / Tim Humphrey
Evaluated 13 Jul 2005

SMC5 and SMC6 genes are required for the segregation of repetitive chromosome regions.
Torres-Rosell J, Machín F, …, Dalgaard JZ, Aragón L
Nat Cell Biol 2005 Apr 7(4):412-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tatsuya Hirano / Matthew O'Connell
Evaluated 13 Jul 2005

Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage.
Sanders SL, Portoso M, …, Allshire RC, Kouzarides T
Cell 2004 Nov 24 119(5):603-14 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Matthew O'Connell / Susan Forsburg / Antony Carr
Evaluated 30 Nov 2004

Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1.
Furuya K, Poitelea M, …, Caspari T, Carr AM
Genes Dev 2004 May 15 18(10):1154-64 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Matthew O'Connell
Evaluated 7 Jul 2004

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