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Miles Wilkinson
Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, United States of America

Faculty Member: CELL BIOLOGY > Control of gene expression [ since 24 August 2001 ]
[ Evaluations ]
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Evaluations

Specificity of ARGONAUTE7-miR390 interaction and dual functionality in TAS3 trans-acting siRNA formation.
Montgomery TA, Howell MD, …, Allen E, Carrington JC
Cell 2008 Apr 4 133(1):128-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 2 May 2008

Following translation by single ribosomes one codon at a time.
Wen JD, Lancaster L, …, Bustamante C, Tinoco I
Nature 2008 Apr 3 452(7187):598-603 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jose Valpuesta / Miles Wilkinson / Sabine Müller
Evaluated 2 May 2008

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Kleinman ME, Yamada K, …, Taylor EW, Ambati J
Nature 2008 Apr 3 452(7187):591-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Bryan Williams / Murali Ramanathan / Richard Vile / Mark Boothby / Miles Wilkinson
Evaluated 2 May 2008


Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide.
Mi S, Cai T, …, Hannon GJ, Qi Y
Cell 2008 Apr 4 133(1):116-27 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 2 May 2008

Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules.
Nunez E, Kwon YS, …, Rosenfeld MG, Fu XD
Cell 2008 Mar 21 132(6):996-1010 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul Kaufman / Rivka Dikstein / Miles Wilkinson
Evaluated 2 May 2008

Pluripotency of a single spermatogonial stem cell in mice.
Kanatsu-Shinohara M, Lee J, …, Ogura A, Shinohara T
Biol Reprod 2008 Apr 78(4):681-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 2 May 2008


MicroRNA-373 induces expression of genes with complementary promoter sequences.
Place RF, Li LC, …, Noonan EJ, Dahiya R
Proc Natl Acad Sci U S A 2008 Feb 5 105(5):1608-13 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 1 May 2008

A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs.
Mellman DL, Gonzales ML, …, Kendziorski C, Anderson RA
Nature 2008 Feb 21 451(7181):1013-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Tom Misteli / Miles Wilkinson / Susan Wente / Gabriele Varani
Evaluated 1 May 2008

The evolution of gene regulation underlies a morphological difference between two Drosophila sister species.
Jeong S, Rebeiz M, …, True J, Carroll SB
Cell 2008 Mar 7 132(5):783-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Artyom Kopp / Miles Wilkinson / Yoav Gilad
Evaluated 1 May 2008

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex.
Han J, Lee Y, …, Zhang BT, Kim VN
Cell 2006 Jun 2 125(5):887-901 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kevin J. Luebke / Miles Wilkinson
Evaluated 21 May 2007

Pachytene asynapsis drives meiotic sex chromosome inactivation and leads to substantial postmeiotic repression in spermatids.
Turner JM, Mahadevaiah SK, …, Mitchell MJ, Burgoyne PS
Dev Cell 2006 Apr 10(4):521-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 18 May 2007

Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors.
Garcia-Bassets I, Kwon YS, …, Fu XD, Rosenfeld MG
Cell 2007 Feb 9 128(3):505-18 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 18 May 2007

Postmeiotic sex chromatin in the male germline of mice.
Namekawa SH, Park PJ, …, Griswold MD, Lee JT
Curr Biol 2006 Apr 4 16(7):660-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 18 May 2007

A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.
Ju BG, Lunyak VV, …, Glass CK, Rosenfeld MG
Science 2006 Jun 23 312(5781):1798-802 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Michael B. Yaffe / Andrew Belmont / Thomas Kodadek / Miles Wilkinson
Evaluated 18 May 2007

Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression.
Cvoro A, Tzagarakis-Foster C, …, Fox MS, Leitman DC
Mol Cell 2006 Feb 17 21(4):555-64 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 18 May 2007

Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Andersen CB, Ballut L, …, Le Hir H, Andersen GR
Science 2006 Sep 29 313(5795):1968-72 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anne-Catherine Dock-Bregeon / Miles Wilkinson
Evaluated 18 May 2007

The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA.
Bono F, Ebert J, Lorentzen E, Conti E
Cell 2006 Aug 25 126(4):713-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lynne Maquat / Megerditch Kiledjian / Anne-Catherine Dock-Bregeon / Reinhard Luehrmann / Daniel Herschlag / Miles Wilkinson
Evaluated 18 May 2007

Transcriptional profiling of androgen receptor (AR) mutants suggests instructive and permissive roles of AR signaling in germ cell development.
Eacker SM, Shima JE, …, Griswold MD, Braun RE
Mol Endocrinol 2007 Apr 21(4):895-907 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 18 May 2007

The proteasome restricts permissive transcription at tissue-specific gene loci in embryonic stem cells.
Szutorisz H, Georgiou A, Tora L, Dillon N
Cell 2006 Dec 29 127(7):1375-88 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas Kodadek / Shiv Pillai / Miles Wilkinson
Evaluated 18 May 2007

Epigenetic characterization of the early embryo with a chromatin immunoprecipitation protocol applicable to small cell populations.
O'Neill LP, VerMilyea MD, Turner BM
Nat Genet 2006 Jul 38(7):835-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Scambler / Michael Meisterernst / Miles Wilkinson
Evaluated 17 May 2007

cis-requirement for the maintenance of round spermatid-specific transcription.
Acharya KK, Govind CK, …, Stoler MH, Reddi PP
Dev Biol 2006 Jul 15 295(2):781-90 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 17 May 2007

Pluripotency of spermatogonial stem cells from adult mouse testis.
Guan K, Nayernia K, …, Engel W, Hasenfuss G
Nature 2006 Apr 27 440(7088):1199-203 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Azim Surani / Ali H. Brivanlou / Miles Wilkinson
Evaluated 17 May 2007


Transcriptional pulsing of a developmental gene.
Chubb JR, Trcek T, Shenoy SM, Singer RH
Curr Biol 2006 May 23 16(10):1018-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jason Swedlow / Roger Patient / Anjana Rao / Richard Gomer / Miles Wilkinson
Evaluated 17 May 2007

Association of ribosomal proteins with nascent transcripts in S. cerevisiae.
Schroder PA, Moore MJ
RNA 2005 Oct 11(10):1521-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 31 Aug 2006

Endonucleolytic cleavage of eukaryotic mRNAs with stalls in translation elongation.
Doma MK, Parker R
Nature 2006 Mar 23 440(7083):561-4 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lynne Maquat / Michael Yarus / Miles Wilkinson
Evaluated 29 Aug 2006

Regulating gene expression through RNA nuclear retention.
Prasanth KV, Prasanth SG, …, Zhang MQ, Spector DL
Cell 2005 Oct 21 123(2):249-63 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Sui Huang / Richard Maraia / Roy Long / Miles Wilkinson
Evaluated 29 Aug 2006

The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron.
Bor YC, Swartz J, …, Ladomery M, Hammarskjöld ML
Genes Dev 2006 Jun 15 20(12):1597-608 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 29 Aug 2006

Exon tethering in transcription by RNA polymerase II.
Dye MJ, Gromak N, Proudfoot NJ
Mol Cell 2006 Mar 17 21(6):849-59 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lawrence Chasin / Benoit Coulombe / Miles Wilkinson
Evaluated 29 Aug 2006

The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.
Gao F, Maiti S, …, Guillou F, Huff V
Proc Natl Acad Sci U S A 2006 Aug 8 103(32):11987-92 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 29 Aug 2006

Epigenetic transgenerational actions of endocrine disruptors and male fertility.
Anway MD, Cupp AS, Uzumcu M, Skinner MK
Science 2005 Jun 3 308(5727):1466-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Joan Ruderman / Achim Peters / Miles Wilkinson
Evaluated 10 Aug 2005

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies.
Liu J, Valencia-Sanchez MA, Hannon GJ, Parker R
Nat Cell Biol 2005 Jul 7(7):719-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Anita Hopper / Miles Wilkinson / Mitzi Kuroda / Robert Sablowski
Evaluated 10 Aug 2005

A microRNA polycistron as a potential human oncogene.
He L, Thomson JM, …, Hannon GJ, Hammond SM
Nature 2005 Jun 9 435(7043):828-33 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Andrew D. Sharrocks / Warren Pear / Miles Wilkinson / David Bilder / Ulf Pettersson
Evaluated 10 Aug 2005

c-Myc-regulated microRNAs modulate E2F1 expression.
O'Donnell KA, Wentzel EA, …, Dang CV, Mendell JT
Nature 2005 Jun 9 435(7043):839-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lucio Comai / Miles Wilkinson
Evaluated 10 Aug 2005

MicroRNA expression profiles classify human cancers.
Lu J, Getz G, …, Horvitz HR, Golub TR
Nature 2005 Jun 9 435(7043):834-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Julie Ahringer / Frank Lyko / Fritz Eckstein / Charles Auffray / Miles Wilkinson
Evaluated 10 Aug 2005

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.
Lim LP, Lau NC, …, Linsley PS, Johnson JM
Nature 2005 Feb 17 433(7027):769-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Isaac Kohane / Harukazu Nakamura / Fritz Eckstein / Ulf Pettersson / Andrew D. Sharrocks / Detlef Weigel / Richard Carthew / Alejandro Sanchez-Alvarado / Vishvanath Nene / Miles Wilkinson
Evaluated 19 Apr 2005

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay.
Kim YK, Furic L, Desgroseillers L, Maquat LE
Cell 2005 Jan 28 120(2):195-208 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Michael Kiebler / Kimberly Mowry / Miles Wilkinson
Evaluated 18 Apr 2005

Involvement of microRNA in AU-rich element-mediated mRNA instability.
Jing Q, Huang S, …, Gram H, Han J
Cell 2005 Mar 11 120(5):623-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Megerditch Kiledjian / Karsten Weis / Miles Wilkinson / Elsebet Lund
Evaluated 18 Apr 2005

eIF4G is required for the pioneer round of translation in mammalian cells.
Lejeune F, Ranganathan AC, Maquat LE
Nat Struct Mol Biol 2004 Oct 11(10):992-1000 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 15 Dec 2004

Nonsense-mediated decay does not occur within the yeast nucleus.
Kuperwasser N, Brogna S, Dower K, Rosbash M
RNA 2004 Dec 10(12):1907-15 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 15 Dec 2004

Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination.
Teixeira A, Tahiri-Alaoui A, …, Proudfoot NJ, Akoulitchev A
Nature 2004 Nov 25 432(7016):526-30 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Arlen Johnson / Miles Wilkinson
Evaluated 15 Dec 2004

Argonaute2 is the catalytic engine of mammalian RNAi.
Liu J, Carmell MA, …, Joshua-Tor L, Hannon GJ
Science 2004 Sep 3 305(5689):1437-41 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Marjori Matzke / Daniel Gallie / Fritz Eckstein / Miles Wilkinson / Richard Carthew
Evaluated 16 Aug 2004

Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay.
Wollerton MC, Gooding C, …, Garcia-Blanco MA, Smith CW
Mol Cell 2004 Jan 16 13(1):91-100 [abstract on PubMed] [related articles] [order article]
Selected by | Miles Wilkinson
Evaluated 13 Aug 2004

Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila.
Gatfield D, Izaurralde E
Nature 2004 Jun 3 429(6991):575-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Elmar Wahle / Lynne Maquat / Miles Wilkinson
Evaluated 13 Aug 2004

The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex.
Chiu SY, Lejeune F, Ranganathan AC, Maquat LE
Genes Dev 2004 Apr 1 18(7):745-54 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lawrence Chasin / Miles Wilkinson
Evaluated 21 Apr 2004

An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay.
Palacios IM, Gatfield D, St Johnston D, Izaurralde E
Nature 2004 Feb 19 427(6976):753-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lynne Maquat / Ilan Davis / Miles Wilkinson / Gabriele Varani
Evaluated 15 Apr 2004

eIF4A3 is a novel component of the exon junction complex.
Chan CC, Dostie J, …, Rappsilber J, Dreyfuss G
RNA 2004 Feb 10(2):200-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lynne Maquat / Miles Wilkinson
Evaluated 15 Apr 2004

A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay.
Ferraiuolo MA, Lee CS, …, Reed R, Sonenberg N
Proc Natl Acad Sci U S A 2004 Mar 23 101(12):4118-23 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 15 Apr 2004

eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay.
Shibuya T, Tange TØ, Sonenberg N, Moore MJ
Nat Struct Mol Biol 2004 Apr 11(4):346-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 14 Apr 2004

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing.
Meister G, Landthaler M, Dorsett Y, Tuschl T
RNA 2004 Mar 10(3):544-50 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Peter Sarnow / Miles Wilkinson / Oliver Hobert
Evaluated 14 Apr 2004

Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein.
Amsellem S, Pflumio F, …, Dubart-Kupperschmitt A, Fichelson S
Nat Med 2003 Nov 9(11):1423-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Alain Prochiantz / Miles Wilkinson
Evaluated 5 Jan 2004

Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.
Zhang Q, Yoshimatsu Y, …, Frisch SM, Goodman RH
Cell 2003 Oct 17 115(2):177-86 [abstract on PubMed] [related articles] [order article]
Selected by | David Wotton / Miles Wilkinson
Evaluated 5 Jan 2004

Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control.
Mazumder B, Sampath P, …, DiCorleto PE, Fox PL
Cell 2003 Oct 17 115(2):187-98 [abstract on PubMed] [related articles] [order article]
Selected by | Christopher Nicchitta / Jonathan R. Warner / Elizabeth Gavis / Miles Wilkinson
Evaluated 5 Jan 2004

The effect of nonsense codons on splicing: a genomic analysis.
Zhang X, Lee J, Chasin LA
RNA 2003 Jun 9(6):637-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 11 Sep 2003

Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeast.
Takahashi S, Araki Y, Sakuno T, Katada T
EMBO J 2003 Aug 1 22(15):3951-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lynne Maquat / Miles Wilkinson
Evaluated 8 Sep 2003

An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation.
Mitchell P, Tollervey D
Mol Cell 2003 May 11(5):1405-13 [abstract on PubMed] [related articles] [order article]
Selected by | Lynne Maquat / Megerditch Kiledjian / Miles Wilkinson
Evaluated 8 Sep 2003

Y14 and hUpf3b form an NMD-activating complex.
Gehring NH, Neu-Yilik G, …, Hentze MW, Kulozik AE
Mol Cell 2003 Apr 11(4):939-49 [abstract on PubMed] [related articles] [order article]
Selected by | Miles Wilkinson
Evaluated 5 Sep 2003

Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery.
Hieronymus H, Silver PA
Nat Genet 2003 Feb 33(2):155-61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Miles Wilkinson
Evaluated 20 Mar 2003

TIA-1 or TIAR is required for DT40 cell viability.
Le Guiner C, Gesnel MC, Breathnach R
J Biol Chem 2003 Mar 21 278(12):10465-76 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson
Evaluated 20 Mar 2003

Nuclear protein synthesis: a re-evaluation.
Nathanson L, Xia T, Deutscher MP
RNA 2003 Jan 9(1):9-13 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lynne Maquat / Miles Wilkinson
Evaluated 21 Jan 2003

Beta -Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon.
Stevens A, Wang Y, …, Schoenberg DR, Maquat LE
Proc Natl Acad Sci U S A 2002 Oct 1 99(20):12741-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Megerditch Kiledjian / Miles Wilkinson
Evaluated 2 Jan 2003

Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.
Lykke-Andersen J
Mol Cell Biol 2002 Dec 22(23):8114-21 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson / Arlen Johnson
Evaluated 2 Jan 2003

5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly.
Reichert VL, Le Hir H, Jurica MS, Moore MJ
Genes Dev 2002 Nov 1 16(21):2778-91 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Miles Wilkinson / Lawrence Chasin
Evaluated 19 Dec 2002

A global analysis of Caenorhabditis elegans operons.
Blumenthal T, Evans D, …, Kiraly M, Kim SK
Nature 2002 Jun 20 417(6891):851-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jonathan Hodgkin / Arcady Mushegian / Miles Wilkinson
Evaluated 26 Nov 2002

In vivo kinetics of mRNA splicing and transport in mammalian cells.
Audibert A, Weil D, Dautry F
Mol Cell Biol 2002 Oct 22(19):6706-18 [abstract on PubMed] [related article