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Harry Ischiropoulos
The Children's Hospital of Philadelphia, Abramson Center, United States of America

Faculty Member: CHEMICAL BIOLOGY > Bioinorganic chemistry [ since 24 June 2002 ]
[ Evaluations ]
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Evaluations

Genetically Encoding Protein Oxidative Damage.
Neumann H, Hazen JL, …, Mehl RA, Chin JW
J Am Chem Soc 2008 Mar 6 0 [abstract on PubMed] [related articles] [full text]
Selected by | Harry Ischiropoulos
Evaluated 12 Mar 2008

Nitrated alpha-Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons.
Benner EJ, Banerjee R, …, Mosley RL, Gendelman HE
PLoS ONE 2008 3(1):e1376 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 9 Jan 2008

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS.
Pandey UB, Nie Z, …, Baehrecke EH, Taylor JP
Nature 2007 Jun 14 447(7146):859-63 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | W. Brent Derry / Thorsten Hoppe / Harry Ischiropoulos / Daniel Klionsky
Evaluated 4 Sep 2007

Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 cells by tyrosine-containing peptides.
Ye Y, Quijano C, …, Beckman JS, Estévez AG
J Biol Chem 2007 Mar 2 282(9):6324-37 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Harry Ischiropoulos
Evaluated 12 Mar 2007

Early inhaled nitric oxide therapy in premature newborns with respiratory failure.
Kinsella JP, Cutter GR, …, Baier M, Abman SH
N Engl J Med 2006 Jul 27 355(4):354-64 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 21 Aug 2006

Inhaled nitric oxide in preterm infants undergoing mechanical ventilation.
Ballard RA, Truog WE, …, Coburn CE, NO CLD Study Group
N Engl J Med 2006 Jul 27 355(4):343-53 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 21 Aug 2006

Neuroprotection by pharmacologic blockade of the GAPDH death cascade.
Hara MR, Thomas B, …, Sawa A, Snyder SH
Proc Natl Acad Sci U S A 2006 Mar 7 103(10):3887-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 3 Apr 2006


Tyrosine nitration by superoxide and nitric oxide fluxes in biological systems: modeling the impact of superoxide dismutase and nitric oxide diffusion.
Quijano C, Romero N, Radi R
Free Radic Biol Med 2005 Sep 15 39(6):728-41 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Harry Ischiropoulos
Evaluated 2 Sep 2005

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein.
Fornai F, Schlüter OM, …, Paparelli A, Südhof TC
Proc Natl Acad Sci U S A 2005 Mar 1 102(9):3413-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 23 May 2005

Red cell membrane and plasma linoleic acid nitration products: synthesis, clinical identification, and quantitation.
Baker PR, Schopfer FJ, Sweeney S, Freeman BA
Proc Natl Acad Sci U S A 2004 Aug 10 101(32):11577-82 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 1 Nov 2004

Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock.
Liu L, Yan Y, …, Que LG, Stamler JS
Cell 2004 Feb 20 116(4):617-28 [abstract on PubMed] [related articles] [order article]
Selected by | Harry Ischiropoulos
Evaluated 13 Apr 2004

Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.
Almeida A, Moncada S, Bolaños JP
Nat Cell Biol 2004 Jan 6(1):45-51 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Harry Ischiropoulos
Evaluated 13 Apr 2004

Analysis of nitrated proteins by nitrotyrosine-specific affinity probes and mass spectrometry.
Nikov G, Bhat V, Wishnok JS, Tannenbaum SR
Anal Biochem 2003 Sep 15 320(2):214-22 [abstract on PubMed] [related articles] [order article]
Selected by | Harry Ischiropoulos
Evaluated 28 Aug 2003

Regulation of beta cell glucokinase by S-nitrosylation and association with nitric oxide synthase.
Rizzo MA, Piston DW
J Cell Biol 2003 Apr 28 161(2):243-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 11 Jun 2003

Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.
Nisoli E, Clementi E, …, Moncada S, Carruba MO
Science 2003 Feb 7 299(5608):896-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 21 Mar 2003

Nitrosopeptide mapping: a novel methodology reveals s-nitrosylation of dexras1 on a single cysteine residue.
Jaffrey SR, Fang M, Snyder SH
Chem Biol 2002 Dec 9(12):1329-35 [abstract on PubMed] [related articles] [order article]
Selected by | Harry Ischiropoulos
Evaluated 24 Jan 2003

Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils.
Lashuel HA, Petre BM, …, Walz T, Lansbury PT
J Mol Biol 2002 Oct 4 322(5):1089-102 [abstract on PubMed] [related articles] [order article]
Selected by | Harry Ischiropoulos
Evaluated 7 Nov 2002

NCX-4016, a nitric oxide-releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function.
Fiorucci S, Mencarelli A, …, del Soldato P, Moncada S
FASEB J 2002 Oct 16(12):1645-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 6 Nov 2002

An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.
Sherer TB, Betarbet R, …, Cookson MR, Greenamyre JT
J Neurosci 2002 Aug 15 22(16):7006-15 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Harry Ischiropoulos
Evaluated 12 Sep 2002

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