Celerino Abad-Zapatero sponsors free access to F1000 for Universidad Nacional Autónoma de México, Mexico. Supporting F1000's initiative to make itself available to scientists in all countries, including free access to developing countries (more details).

Structural basis for selective inhibition of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB. Grundner C, Perrin D, …, Wells TN, Alber T Structure 2007 Apr 15(4):499-509 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 21 Nov 2007 Modulation of Spc1 stress-activated protein kinase activity by methylglyoxal through inhibition of protein phosphatase in the fission yeast Schizosaccharomyces pombe. Takatsume Y, Izawa S, Inoue Y Biochem Biophys Res Commun 2007 Nov 30 363(4):942-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 16 Nov 2007 2-Aryl-3,3,3-trifluoro-2-hydroxypropionic acids: A new class of protein tyrosine phosphatase 1B inhibitors. Adams DR, Abraham A, …, Spinks D, Takano Y Bioorg Med Chem Lett 2007 Dec 1 17(23):6579-83 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Peter Wipf / Celerino Abad-Zapatero Evaluated 14 Nov 2007 An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site. Rock FL, Mao W, …, Cusack S, Alley MR Science 2007 Jun 22 316(5832):1759-61 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero / Xiayang Qiu / Dennis Hall / Anne-Catherine Dock-Bregeon Evaluated 27 Jun 2007 Femtosecond diffractive imaging with a soft-X-ray free-electron laser. Chapman HN, Barty A, …, Timneanu N, Hajdu J Nat Phys 2006 2:839-843 [full text] Selected by | Celerino Abad-Zapatero Evaluated 2 Apr 2007 Differential redox regulation within the PTP superfamily. Ross SH, Lindsay Y, …, Downes CP, Leslie NR Cell Signal 2007 Jul 19(7):1521-30 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 21 Mar 2007 A brake becomes an accelerator: PTP1B--a new therapeutic target for breast cancer. Tonks NK, Muthuswamy SK Cancer Cell 2007 Mar 11(3):214-6 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 21 Mar 2007 The natural product berberine is a human prolyl oligopeptidase inhibitor. Tarrago T, Kichik N, Seguí J, Giralt E ChemMedChem 2007 Mar 2(3):354-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 27 Feb 2007 DrugBank: a comprehensive resource for in silico drug discovery and exploration. Wishart DS, Knox C, …, Chang Z, Woolsey J Nucleic Acids Res 2006-01-01 34(Database issue):D668-72 [abstract on PubMed] [related articles] [FREE full text] Selected by | Celerino Abad-Zapatero / John Proudfoot Evaluated 16 Nov 2006 Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Nören-Müller A, Reis-Corrêa I, …, Schiewe H, Waldmann H Proc Natl Acad Sci U S A 2006 Jul 11 103(28):10606-11 [abstract on PubMed] [related articles] [FREE full text] Selected by | Celerino Abad-Zapatero Evaluated 31 Aug 2006 Reactive oxygen species have a causal role in multiple forms of insulin resistance. Houstis N, Rosen ED, Lander ES Nature 2006 Apr 13 440(7086):944-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Robert Sapolsky / Celerino Abad-Zapatero Evaluated 4 Jul 2006 Dependence of molecular properties on proteomic family for marketed oral drugs. Vieth M, Sutherland JJ J Med Chem 2006 Jun 15 49(12):3451-3 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero / John Saunders Evaluated 1 Jun 2006 X-ray Structure of a self-compartmentalizing sulfur cycle metalloenzyme. Urich T, Gomes CM, Kletzin A, Frazão C Science 2006 Feb 17 311(5763):996-1000 [abstract on PubMed] [related articles] [FREE full text] Selected by | Joan Broderick / Dianne Newman / Andrea Mattevi / Celerino Abad-Zapatero Evaluated 4 Apr 2006 Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors. Moretto AF, Kirincich SJ, …, Tam SY, Lee J Bioorg Med Chem 2006 Apr 1 14(7):2162-77 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 5 Dec 2005 Protein structures forming the shell of primitive bacterial organelles. Kerfeld CA, Sawaya MR, …, Beeby M, Yeates TO Science 2005 Aug 5 309(5736):936-8 [abstract on PubMed] [related articles] [FREE full text] Selected by | Tony Crowther / Edward Egelman / Celerino Abad-Zapatero Evaluated 25 Oct 2005 Structural biology and drug discovery. Congreve M, Murray CW, Blundell TL Drug Discov Today 2005 Jul 1 10(13):895-907 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 9 Aug 2005 Genes that mediate breast cancer metastasis to lung. Minn AJ, Gupta GP, …, Gerald WL, Massagué J Nature 2005 Jul 28 436(7050):518-24 [abstract on PubMed] [related articles] [FREE full text] Selected by | Anthony Means / Celerino Abad-Zapatero / Kenneth Yamada / Jenny Ting / Charles Streuli Evaluated 9 Aug 2005 The temperature of flash-cooling has dramatic effects on the diffraction quality of nucleosome crystals. Edayathumangalam RS, Luger K Acta Crystallogr D Biol Crystallogr 2005 Jul 61(Pt 7):891-8 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 20 Jul 2005 Metal specificity is correlated with two crucial active site residues in Escherichia coli alkaline phosphatase. Wang J, Stieglitz KA, Kantrowitz ER Biochemistry 2005 Jun 14 44(23):8378-86 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 20 Jul 2005 Structure of the rotor of the V-Type Na+-ATPase from Enterococcus hirae. Murata T, Yamato I, …, Leslie AG, Walker JE Science 2005 Apr 29 308(5722):654-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Wolfgang Junge / Robert Fillingame / Celerino Abad-Zapatero / Petra Fromme Evaluated 6 May 2005 Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Jaeschke A, Rincón M, …, Flavell RA, Davis RJ Proc Natl Acad Sci U S A 2005 May 10 102(19):6931-5 [abstract on PubMed] [related articles] [FREE full text] Selected by | Celerino Abad-Zapatero Evaluated 6 May 2005 JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Wang MC, Bohmann D, Jasper H Cell 2005 Apr 8 121(1):115-25 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero / Norbert Perrimon / Stephen Helfand Evaluated 4 Apr 2005 Amyloid-like properties of bacterial inclusion bodies. Carrió M, González-Montalbán N, …, Villaverde A, Ventura S J Mol Biol 2005 Apr 15 347(5):1025-37 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 4 Apr 2005 Identification of an antimalarial synthetic trioxolane drug development candidate. Vennerstrom JL, Arbe-Barnes S, …, Wittlin S, Charman WN Nature 2004 Aug 19 430(7002):900-4 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Michael Gelb / Celerino Abad-Zapatero Evaluated 1 Oct 2004 Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Mougous JD, Petzold CJ, …, Berger JM, Bertozzi CR Nat Struct Mol Biol 2004 Aug 11(8):721-9 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 1 Oct 2004 Allosteric inhibition of protein tyrosine phosphatase 1B. Wiesmann C, Barr KJ, …, McDowell RS, Hansen SK Nat Struct Mol Biol 2004 Aug 11(8):730-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Stevan Hubbard / Celerino Abad-Zapatero / Wolfgang Jahnke / Zhong-Yin Zhang / Amy Barrios Evaluated 30 Jul 2004 Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. Meng TC, Buckley DA, …, Tiganis T, Tonks NK J Biol Chem 2004 Sep 3 279(36):37716-25 [abstract on PubMed] [related articles] [FREE full text] Selected by | Celerino Abad-Zapatero Evaluated 25 Jun 2004 Catalytic inactivation of protein tyrosine phosphatase CD45 and protein tyrosine phosphatase 1B by polyaromatic quinones. Wang Q, Dubé D, …, Gresser MJ, Huang Z Biochemistry 2004 Apr 13 43(14):4294-303 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 5 May 2004 Conformational analysis of drug-like molecules bound to proteins: an extensive study of ligand reorganization upon binding. Perola E, Charifson PS J Med Chem 2004 May 6 47(10):2499-510 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 13 Apr 2004 Beyond the metabolic function of PTP1B. Dubé N, Tremblay ML Cell Cycle 2004 May 3(5):550-3 [abstract on PubMed] [related articles] [FREE full text] Selected by | Celerino Abad-Zapatero Evaluated 13 Apr 2004 The tylosin-resistance methyltransferase RlmA(II) (TlrB) modifies the N-1 position of 23S rRNA nucleotide G748. Douthwaite S, Crain PF, Liu M, Poehlsgaard J J Mol Biol 2004 Apr 9 337(5):1073-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 13 Apr 2004 Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS. Pantazatos D, Kim JS, …, Lesley SA, Woods VL Proc Natl Acad Sci U S A 2004 Jan 20 101(3):751-6 [abstract on PubMed] [related articles] [FREE full text] Selected by | Patricia C. Weber / Celerino Abad-Zapatero / Song Tan / David Waugh Evaluated 30 Jan 2004 Structural insights into molecular function of the metastasis-associated phosphatase PRL-3. Kozlov G, Cheng J, …, Gehring K, Ekiel I J Biol Chem 2004 Mar 19 279(12):11882-9 [abstract on PubMed] [related articles] [FREE full text] Selected by | Celerino Abad-Zapatero Evaluated 22 Jan 2004 Formation of disulfide bond in p53 correlates with inhibition of DNA binding and tetramerization. Sun XZ, Vinci C, …, Thomas J, Momand J Antioxid Redox Signal 2003 Oct 5(5):655-65 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Celerino Abad-Zapatero Evaluated 10 Dec 2003 Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase. Masubuchi M, Ebiike H, …, Ohtsuka T, Shimma N Bioorg Med Chem 2003 Oct 1 11(20):4463-78 [abstract on PubMed] [related articles] [order article] Selected by | Celerino Abad-Zapatero Evaluated 3 Oct 2003 Structural basis for the product specificity of histone lysine methyltransferases. Zhang X, Yang Z, …, Selker EU, Cheng X Mol Cell 2003 Jul 12(1):177-85 [abstract on PubMed] [related articles] [order article] Selected by | Robert Dutnall / Thomas Jenuwein / Celerino Abad-Zapatero Evaluated 29 Sep 2003 Metal and redox modulation of cysteine protein function. Giles NM, Watts AB, …, Littlechild JA, Jacob C Chem Biol 2003 Aug 10(8):677-93 [abstract on PubMed] [related articles] [order article] Selected by | Celerino Abad-Zapatero Evaluated 29 Sep 2003 Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family. Zubieta C, Ross JR, …, Pichersky E, Noel JP Plant Cell 2003 Aug 15(8):1704-16 [abstract on PubMed] [related articles] [FREE full text] Selected by | Celerino Abad-Zapatero Evaluated 22 Aug 2003 Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B. van Montfort RL, Congreve M, …, Carr R, Jhoti H Nature 2003 Jun 12 423(6941):773-7 [abstract on PubMed] [related articles] [full text] [order article] Selected by | Zhong-Yin Zhang / Celerino Abad-Zapatero / Douglas Freymann Evaluated 24 Jun 2003

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