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Matthew Breyer
Biotechnology Discovery Research, Lilly Research Laboratories, Indianapolis, United States of America

Faculty Member: PHYSIOLOGY > Renal, fluid & electrolyte physiology [ since 19 January 2005 ]
[ Evaluations ]
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Evaluations

The Notch pathway in podocytes plays a role in the development of glomerular disease.
Niranjan T, Bielesz B, …, Thomas DB, Susztak K
Nat Med 2008 Mar 14(3):290-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Matthew Breyer / Moshe Levi
Evaluated 27 Mar 2008


Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.
Higgins DF, Kimura K, …, Iwano M, Haase VH
J Clin Invest 2007 Dec 117(12):3810-20 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Matthew Breyer
Evaluated 1 Feb 2008

Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
Groenestege WM, Thébault S, …, Knoers NV, Bindels RJ
J Clin Invest 2007 Aug 117(8):2260-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Matthew Breyer
Evaluated 11 Sep 2007

The effect of angiotensin II receptor blockade on an end-stage renal failure model of type 2 diabetes.
Mizuno M, Sada T, …, Terashima H, Koike H
J Cardiovasc Pharmacol 2006 Oct 48(4):135-42 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Matthew Breyer
Evaluated 17 Apr 2007

Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.
Crowley SD, Gurley SB, …, Le TH, Coffman TM
Proc Natl Acad Sci U S A 2006 Nov 21 103(47):17985-90 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Matthew Breyer / Soeren Sheikh / Raymond Harris / Anna Dominiczak / Tom Lohmeier / David J Webb / Robert Carey
Evaluated 17 Nov 2006


Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.
Clee SM, Yandell BS, …, Flowers MT, Attie AD
Nat Genet 2006 Jun 38(6):688-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Matthew Breyer
Evaluated 27 Oct 2006

Activated signal transduction kinases frequently occupy target genes.
Pokholok DK, Zeitlinger J, …, Reynolds DB, Young RA
Science 2006 Jul 28 313(5786):533-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ilaria Rebay / Anthony Means / Giulio Superti-Furga / Matthew Breyer / Sjur Olsnes / David Levin
Evaluated 24 Aug 2006

Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.
Uno K, Katagiri H, …, Nakazato M, Oka Y
Science 2006 Jun 16 312(5780):1656-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Carl Thummel / Matthew Breyer / Michael Andresen
Evaluated 3 Jul 2006

A distal enhancer and an ultraconserved exon are derived from a novel retroposon.
Bejerano G, Lowe CB, …, Kent WJ, Haussler D
Nature 2006 May 4 441(7089):87-90 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jim Thomas / Matthew Breyer
Evaluated 17 May 2006

Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function.
Cheng Y, Wang M, …, Funk CD, Fitzgerald GA
J Clin Invest 2006 May 116(5):1391-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Matthew Breyer
Evaluated 28 Apr 2006

Retrospective birth dating of cells in humans.
Spalding KL, Bhardwaj RD, …, Druid H, Frisén J
Cell 2005 Jul 15 122(1):133-43 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Carl Thummel / Lars-Eric Thornell / Matthew Breyer
Evaluated 1 Mar 2006

Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2.
Kim SF, Huri DA, Snyder SH
Science 2005 Dec 23 310(5756):1966-70 [abstract on PubMed] [related articles] [FREE full text]
Selected by | David Robertson / Matthew Breyer
Evaluated 13 Jan 2006

Mitogenic influence of human R-spondin1 on the intestinal epithelium.
Kim KA, Kakitani M, …, Funk WD, Tomizuka K
Science 2005 Aug 19 309(5738):1256-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kermit Carraway / Matthew Breyer
Evaluated 29 Nov 2005

Suppression of aging in mice by the hormone Klotho.
Kurosu H, Yamamoto M, …, Rosenblatt KP, Kuro-o M
Science 2005 Sep 16 309(5742):1829-33 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Matthew Breyer / William H. Colledge / Thomas Nystrom
Evaluated 16 Sep 2005

Vascular respiratory uncoupling increases blood pressure and atherosclerosis.
Bernal-Mizrachi C, Gates AC, …, Muglia LJ, Semenkovich CF
Nature 2005 May 26 435(7041):502-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Daniel Ricquier / Matthew Breyer / Fabio Recchia
Dissenters | Eduardo Rial
Evaluated 9 Jun 2005


The MET oncogene drives a genetic programme linking cancer to haemostasis.
Boccaccio C, Sabatino G, …, Naldini L, Comoglio PM
Nature 2005 Mar 17 434(7031):396-400 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Matthew Breyer
Evaluated 4 Apr 2005

Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron.
Flo TH, Smith KD, …, Akira S, Aderem A
Nature 2004 Dec 16 432(7019):917-21 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dehua Pei / Pascale Cossart / Andreas Baumler / Brigitte Gicquel / Caroline Philpott / Matthew Breyer
Evaluated 8 Mar 2005

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