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Ueli Schibler
Department of Molecular Biology, University of Geneva, Geneva, Switzerland

Faculty Member: CELL BIOLOGY > Control of gene expression [ since 25 July 2001 ]
[ Evaluations ]
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Evaluations

Circadian transcription contributes to core period determination in Drosophila.
Kadener S, Menet JS, Schoer R, Rosbash M
PLoS Biol 2008 May 20 6(5):e119 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 19 Jun 2008

Sympathetic input modulates, but does not determine, phase of peripheral circadian oscillators.
Vujovic N, Davidson AJ, Menaker M
Am J Physiol Regul Integr Comp Physiol 2008 Apr 23 [abstract on PubMed] [related articles] [full text]
Selected by | Ueli Schibler
Evaluated 19 Jun 2008

Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision.
Güler AD, Ecker JL, …, Yau KW, Hattar S
Nature 2008 May 1 453(7191):102-5 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 19 Jun 2008

Melatonin suppresses nighttime memory formation in zebrafish.
Rawashdeh O, de Borsetti NH, Roman G, Cahill GM
Science 2007 Nov 16 318(5853):1144-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 17 Jan 2008

Splicing segregation: the minor spliceosome acts outside the nucleus and controls cell proliferation.
König H, Matter N, …, Thiele W, Müller F
Cell 2007 Nov 16 131(4):718-29 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler / Charles Query
Evaluated 17 Jan 2008

Circadian transcription depends on limiting amounts of the transcription co-activator nejire/CBP.
Hung HC, Maurer C, Kay SA, Weber F
J Biol Chem 2007 Oct 26 282(43):31349-57 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 15 Aug 2007

Peripheral circadian oscillators require CLOCK.
DeBruyne JP, Weaver DR, Reppert SM
Curr Biol 2007 Jul 17 17(14):R538-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 15 Aug 2007

Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo.
Pedersen TA, Bereshchenko O, …, Porse BT, Nerlov C
EMBO J 2007 Feb 21 26(4):1081-93 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 10 Apr 2007

Elucidating the ticking of an in vitro circadian clockwork.
Mori T, Williams DR, …, Stewart PL, Johnson CH
PLoS Biol 2007 Apr 5(4):e93 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 10 Apr 2007

Lack of food anticipation in Per2 mutant mice.
Feillet CA, Ripperger JA, …, Albrecht U, Challet E
Curr Biol 2006 Oct 24 16(20):2016-22 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler / Ralf Jockers / Shimon Amir
Evaluated 23 Nov 2006

A map of recent positive selection in the human genome.
Voight BF, Kudaravalli S, Wen X, Pritchard JK
PLoS Biol 2006 Mar 4(3):e72 [abstract on PubMed] [related articles] [FREE full text]
Selected by | James Fry / Joshua Akey / Michael Nachman / Ueli Schibler
Evaluated 21 Apr 2006

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation.
Watanabe M, Houten SM, …, Bianco AC, Auwerx J
Nature 2006 Jan 26 439(7075):484-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler / Evi Kostenis
Evaluated 25 Jan 2006


PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock.
Meyer P, Saez L, Young MW
Science 2006 Jan 13 311(5758):226-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 25 Jan 2006

Phosphorylation-dependent maturation of Neurospora circadian clock protein from a nuclear repressor toward a cytoplasmic activator.
Schafmeier T, Káldi K, …, Mohr C, Brunner M
Genes Dev 2006 Feb 1 20(3):297-306 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 24 Jan 2006

Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin.
Kravchenko JE, Rogozin IB, Koonin EV, Chumakov PM
Nature 2005 Aug 4 436(7051):735-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler / Carl Thummel / Pamela Geyer / Cheng-Ming Chiang / Tony Weil
Evaluated 12 Aug 2005

Transcriptional feedback of Neurospora circadian clock gene by phosphorylation-dependent inactivation of its transcription factor.
Schafmeier T, Haase A, …, Fuchs M, Brunner M
Cell 2005 Jul 29 122(2):235-46 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler / Michael Rosbash
Evaluated 11 Aug 2005

Constant light desynchronizes mammalian clock neurons.
Ohta H, Yamazaki S, McMahon DG
Nat Neurosci 2005 Mar 8(3):267-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 29 Apr 2005

Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro.
Nakajima M, Imai K, …, Oyama T, Kondo T
Science 2005 Apr 15 308(5720):414-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | C. Robertson McClung / Ueli Schibler / Martin Egli / Katherine Osteryoung / Seth J Davis
Evaluated 28 Apr 2005

Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain.
Grima B, Chélot E, Xia R, Rouyer F
Nature 2004 Oct 14 431(7010):869-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 8 Dec 2004

Coupled oscillators control morning and evening locomotor behaviour of Drosophila.
Stoleru D, Peng Y, Agosto J, Rosbash M
Nature 2004 Oct 14 431(7010):862-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 8 Dec 2004

Topological domain structure of the Escherichia coli chromosome.
Postow L, Hardy CD, Arsuaga J, Cozzarelli NR
Genes Dev 2004 Jul 15 18(14):1766-79 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 7 Dec 2004

No transcription-translation feedback in circadian rhythm of KaiC phosphorylation.
Tomita J, Nakajima M, Kondo T, Iwasaki H
Science 2005 Jan 14 307(5707):251-4 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler / Michael Rosbash / C. Robertson McClung
Evaluated 7 Dec 2004

Dicer is essential for formation of the heterochromatin structure in vertebrate cells.
Fukagawa T, Nogami M, …, Nakayama T, Oshimura M
Nat Cell Biol 2004 Aug 6(8):784-91 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 9 Sep 2004

Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain.
Radhakrishnan A, Sun LP, …, Brown MS, Goldstein JL
Mol Cell 2004 Jul 23 15(2):259-68 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 8 Sep 2004

Circadian clock mutation disrupts estrous cyclicity and maintenance of pregnancy.
Miller BH, Olson SL, …, Horton TH, Takahashi JS
Curr Biol 2004 Aug 10 14(15):1367-73 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 3 Sep 2004

The adaptive value of circadian clocks: an experimental assessment in cyanobacteria.
Woelfle MA, Ouyang Y, Phanvijhitsiri K, Johnson CH
Curr Biol 2004 Aug 24 14(16):1481-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 3 Sep 2004

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation.
Dor Y, Brown J, Martinez OI, Melton DA
Nature 2004 May 6 429(6987):41-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Patrick Tam / Anthony Means / Ueli Schibler
Evaluated 19 May 2004

A genomewide oscillation in transcription gates DNA replication and cell cycle.
Klevecz RR, Bolen J, Forrest G, Murray DB
Proc Natl Acad Sci U S A 2004 Feb 3 101(5):1200-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 23 Mar 2004

Negative feedback regulation ensures the one receptor-one olfactory neuron rule in mouse.
Serizawa S, Miyamichi K, …, Yoshihara Y, Sakano H
Science 2003 Dec 19 302(5653):2088-94 [abstract on PubMed] [related articles] [FREE full text]
Selected by | John Ngai / Ueli Schibler / Wilhelm Boland
Evaluated 22 Dec 2003

Light regulates the cell cycle in zebrafish.
Dekens MP, Santoriello C, …, Whitmore D, Foulkes NS
Curr Biol 2003 Dec 2 13(23):2051-7 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler / Julian Lewis
Evaluated 22 Dec 2003

Multiple oscillators regulate circadian gene expression in Neurospora.
Correa A, Lewis ZA, …, Gomer RH, Bell-Pedersen D
Proc Natl Acad Sci U S A 2003 Nov 11 100(23):13597-602 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 22 Dec 2003

S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.
Zheng L, Roeder RG, Luo Y
Cell 2003 Jul 25 114(2):255-66 [abstract on PubMed] [related articles] [order article]
Selected by | Ronald Conaway / Dinah Singer / Ueli Schibler / Stephen Dalton / Patrick Matthias / Michael Meisterernst / Andrew D. Sharrocks
Evaluated 14 Aug 2003

Chromosome cohesion is regulated by a clock gene paralogue TIM-1.
Chan RC, Chan A, …, Rougvie AE, Meyer BJ
Nature 2003 Jun 26 423(6943):1002-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 5 Aug 2003

The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter.
Johnson SM, Lin SY, Slack FJ
Dev Biol 2003 Jul 15 259(2):364-79 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler
Evaluated 5 Aug 2003

Melanopsin is required for non-image-forming photic responses in blind mice.
Panda S, Provencio I, …, Van Gelder RN, Hogenesch JB
Science 2003 Jul 25 301(5632):525-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 5 Aug 2003

Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice.
Hattar S, Lucas RJ, …, Foster RG, Yau KW
Nature 2003 Jul 3 424(6944):76-81 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ueli Schibler
Evaluated 5 Aug 2003

Suprachiasmatic nucleus grafts restore circadian behavioral rhythms of genetically arrhythmic mice.
Sujino M, Masumoto KH, …, Okamura H, Inouye ST
Curr Biol 2003 Apr 15 13(8):664-8 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler
Evaluated 4 Jun 2003

Illuminating the circadian clock in monarch butterfly migration.
Froy O, Gotter AL, Casselman AL, Reppert SM
Science 2003 May 23 300(5623):1303-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 4 Jun 2003

Removing the vertebrate-specific TBP N terminus disrupts placental beta2m-dependent interactions with the maternal immune system.
Hobbs NK, Bondareva AA, …, Capecchi MR, Schmidt EE
Cell 2002 Jul 12 110(1):43-54 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler
Evaluated 21 Feb 2003

Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation.
Jeong JW, Bae MK, …, Lee KJ, Kim KW
Cell 2002 Nov 27 111(5):709-20 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler
Evaluated 3 Feb 2003

NPAS2: a gas-responsive transcription factor.
Dioum EM, Rutter J, …, Gilles-Gonzalez MA, McKnight SL
Science 2002 Dec 20 298(5602):2385-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 17 Jan 2003

The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).
Schreiber SN, Knutti D, …, Uhlmann T, Kralli A
J Biol Chem 2003 Mar 14 278(11):9013-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 16 Jan 2003

Metastable epialleles in mammals.
Rakyan VK, Blewitt ME, …, Preis JI, Whitelaw E
Trends Genet 2002 Jul 18(7):348-51 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler
Evaluated 24 Oct 2002

Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant mice.
Oster H, Yasui A, van der Horst GT, Albrecht U
Genes Dev 2002 Oct 15 16(20):2633-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 23 Oct 2002

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.
Ishizuka A, Siomi MC, Siomi H
Genes Dev 2002 Oct 1 16(19):2497-508 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 23 Oct 2002

A microRNA in a multiple-turnover RNAi enzyme complex.
Hutvágner G, Zamore PD
Science 2002 Sep 20 297(5589):2056-60 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler / Witold Filipowicz / Daniel Gallie / James Carrington
Evaluated 15 Aug 2002

The VPAC(2) receptor is essential for circadian function in the mouse suprachiasmatic nuclei.
Harmar AJ, Marston HM, …, Maywood ES, Hastings MH
Cell 2002 May 17 109(4):497-508 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler
Evaluated 13 Aug 2002

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein.
Kondo K, Klco J, …, Lechpammer M, Kaelin WG
Cancer Cell 2002 Apr 1(3):237-46 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler / Peter Ratcliffe
Evaluated 12 Aug 2002

The photopigment melanopsin is exclusively present in pituitary adenylate cyclase-activating polypeptide-containing retinal ganglion cells of the retinohypothalamic tract.
Hannibal J, Hindersson P, …, Georg B, Fahrenkrug J
J Neurosci 2002 Jan 1 22(1):RC191 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 9 Apr 2002

Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity.
Hattar S, Liao HW, …, Berson DM, Yau KW
Science 2002 Feb 8 295(5557):1065-70 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Roger Hardie / Silvia Arber / S. Murray Sherman / Ueli Schibler
Evaluated 9 Apr 2002

Phototransduction by retinal ganglion cells that set the circadian clock.
Berson DM, Dunn FA, Takao M
Science 2002 Feb 8 295(5557):1070-3 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Roger Hardie / S. Murray Sherman / Ueli Schibler
Evaluated 9 Apr 2002

The SREBP pathway in Drosophila: regulation by palmitate, not sterols.
Seegmiller AC, Dobrosotskaya I, …, Brown MS, Rawson RB
Dev Cell 2002 Feb 2(2):229-38 [abstract on PubMed] [related articles] [order article]
Selected by | Ueli Schibler
Evaluated 4 Apr 2002

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch.
Lando D, Peet DJ, …, Gorman JJ, Whitelaw ML
Science 2002 Feb 1 295(5556):858-61 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ronald Conaway / Ueli Schibler
Evaluated 3 Apr 2002

DREAM is a critical transcriptional repressor for pain modulation.
Cheng HY, Pitcher GM, …, Salter MW, Penninger JM
Cell 2002 Jan 11 108(1):31-43 [abstract on PubMed] [related articles] [order article]
Selected by | Stephen McMahon / Ueli Schibler / Peggy Mason
Evaluated 24 Jan 2002

Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling.
Kramer A, Yang FC, …, Davis FC, Weitz CJ
Science 2001 Dec 21 294(5551):2511-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ueli Schibler
Evaluated 22 Jan 2002

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity.
Mahon PC, Hirota K, Semenza GL
Genes Dev 2001 Oct 15 15(20):2675-86 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ronald Conaway / Ueli Schibler
Evaluated 13 Nov 2001

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.
Epstein AC, Gleadle JM, …, Schofield CJ, Ratcliffe PJ
Cell 2001 Oct 5 107(1):43-54 [abstract on PubMed] [related articles] [order article]
Selected by | Stefan Jentsch / Ronald Conaway / William Kaelin / Ueli Schibler / David Greenstein / Andrius Kazlauskas / Christer Betsholtz
Evaluated 7 Nov 2001

A conserved family of prolyl-4-hydroxylases that modify HIF.
Bruick RK, McKnight SL
Science 2001 Nov 9 294(5545):1337-40 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Ronald Conaway / William Kaelin / Ueli Schibler
Evaluated 7 Nov 2001

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